Collagenase Type IV
For digestion of native collagen fibrils.
- Maintain receptor integrity with a collagenase preparation low in tryptic activity
- Dissociate pancreatic islet cells effectively
Digest native collagen fibrils in connective tissues with Collagenase Type IV, sourced from Clostridium histolyticum. Collagenase preparations typically contain the activity of several proteases, including collagenase, caseinase, clostripain, and trypsin (Kessler and Yaron). Frequently used to dissociate pancreatic islets (Taguchi et al.), and in applications where maintenance of receptor integrity is required, Collagenase Type IV has low tryptic activity compared to other collagenase preparations.
: Product Restrictions: (i) Customer shall not make products or any portion of them, in any way, shape or form, including as a component of another product available for the purpose of further resale or alter or remove the Product label and the Supplier’s mark of origin without express written permission of Supplier; and (ii) Customer is familiar with Supplier’s restrictions on the use of the Products and shall use the Products in compliance with such restrictions and the applicable Supplier Product Information sheet (collectively, the 'Product Restrictions').
- Species:Non-human primateHumanRatMouse
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