Falcon® cell culture inserts coated with collagen.

Cell culture on permeable membranes permits diffusion of media components to both apical and basolateral cell surfaces similar to the in vivo process. Membranes with extracellular matrix (ECM) further improve in vitro cell culture systems by providing cells with a vital component of their microenvironment in vivo. Typical applications for Corning® BioCoat™ cell culture inserts include promotion of epithelial cell polarity; differentiation of a variety of cell types; transport and permeability studies; transendothelial migration, tumour cell invasion assays, in vitro toxicology; and co-culture studies.