Specifications
- Antibody type:Primary
- Antigen name:Mediator of RNA polymerase II transcription subunit 14
- Antigen symbol:MED14
- Clonality:Polyclonal
- Conjugation:Unconjugated
- Host:Rabbit
- Reactivity:Mouse
- Western blot:Yes
- Epitope:Amino Acid Range = 586-615
- Form:Liquid
- Gene ID:O60244
- Antigen synonyms:MED14
- Modification:None
- Storage buffer:Supplied in PBS with 0,09% (W/V) sodium azide
- Molecular weight:161 kDa
- Storage temperature:Store at 4 °C for three months and –20 °C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Concentration:0,25 mg/ml
- Shipping temperature:4 °C
- Immunogen:This MED14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 586-615 amino acids from the Central region of human MED14.
- Purification:This antibody is purified through a protein A column, followed by peptide affinity purification.
- Size:400 µl
- Pk:400 µl
Specifications
About this item
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein contains a bipartite nuclear localization signal. This gene is known to escape chromosome X-inactivation.
For WB starting dilution is: 1:1000.
Type: Primary
Antigen: MED14
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: Rabbit Ig
Reactivity: Mouse