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Anti-MED14 Rabbit Polyclonal Antibody
Anti-MED14 Rabbit Polyclonal Antibody
Catalog # PRSI56-277
Supplier:  ProSci Inc.
New Product
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Anti-MED14 Rabbit Polyclonal Antibody
Catalog # PRSI56-277
Supplier:  ProSci Inc.
New Product

Specifications

  • Antibody type:
    Primary
  • Antigen name:
    Mediator of RNA polymerase II transcription subunit 14
  • Antigen symbol:
    MED14
  • Clonality:
    Polyclonal
  • Conjugation:
    Unconjugated
  • Host:
    Rabbit
  • Reactivity:
    Mouse
  • Western blot:
    Yes
  • Epitope:
    Amino Acid Range = 586-615
  • Form:
    Liquid
  • Gene ID:
    O60244
  • Antigen synonyms:
    MED14
  • Modification:
    None
  • Storage buffer:
    Supplied in PBS with 0,09% (W/V) sodium azide
  • Molecular weight:
    161 kDa
  • Storage temperature:
    Store at 4 °C for three months and –20 °C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Concentration:
    0,25 mg/ml
  • Shipping temperature:
    4 °C
  • Immunogen:
    This MED14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 586-615 amino acids from the Central region of human MED14.
  • Purification:
    This antibody is purified through a protein A column, followed by peptide affinity purification.
  • Size:
    400 µl
  • Pk:
    400 µl

Specifications

About this item

The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein contains a bipartite nuclear localization signal. This gene is known to escape chromosome X-inactivation.

For WB starting dilution is: 1:1000.

Type: Primary
Antigen: MED14
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: Rabbit Ig
Reactivity: Mouse