Specifications
- Antibody type:Primary
- Antigen name:CD44 molecule (Indian blood group)
- Antigen symbol:CD44
- Clonality:Monoclonal
- Clone:IM7
- Conjugation:VioletFluor® 450
- Flow cytometry:Yes
- Host:Rat
- Isotype:IgG2b kappa
- Reactivity:Human,Mouse
- Cross adsorption:No
- Form:liquid
- Gene ID:P16070; P15379
- Antigen synonyms:CD44
- Storage buffer:Phosphate-buffered aqueous solution, ≤0,09% Sodium azide, may contain carrier protein/stabiliser, ph 7,2.
- Storage temperature:The product should be stored undiluted at 4 °C and should be protected from prolonged exposure to light. Do not freeze.
- Shipping temperature:4 °C
- Purification:The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
- Pk:0,025 mg
Specifications
About this item
The IM7 monoclonal antibody specifically reacts with all the isoforms and both alloantigens of the CD44 glycoprotein (Pgp-1, Ly-24). CD44 is expressed on hematopoietic and non-hematopoietic cells, bone marrow myeloid cells, memory T lymphocytes, periphery activated B cells, CD4+ T lymphocytes, and CD8+ T lymphocytes. The periphery B and T lymphocytes upregulate the expression of CD44. CD44 binds to hyaluronan molecules, acting as an adhesion molecule.The IM7 antibody inhibits collagen-induced arthritis in DBA/1 mice, prevents central nervous system inflammation associated with experimental autoimmune encephalomyelitis, but exacerbates the experimental autoimmune thyroiditis in CBA/J mice. The IM7 antibody also cross-reacts with dog, human, pig, horse, cat, and cow leukocytes.BG Violet 450 conjugate is an alternative to the Pacific Blue, eFluor 450, or BD Horizon V450 dyes. It is excited by the violet (405 nm) laser, with a peak emission of 450 nm.
Type: Primary
Antigen: CD44
Clonality: Monoclonal
Clone: IM7
Conjugation: VioletFluor® 450
Epitope:
Host: Rat
Isotype: IgG2b kappa
Reactivity: Human;Mouse