- Antibody type:Primary
- Antigen name:CD19 antigen
- Antigen symbol:Cd19
- Clonality:Monoclonal
- Clone:1D3
- Conjugation:Biotin
- Flow cytometry:Yes
- Host:Rat
- Isotype:IgG2a kappa
- Cross adsorption:No
- Form:liquid
- Gene ID:P25918
- Antigen synonyms:Cd19
- Storage buffer:Phosphate-buffered aqueous solution, ≤0,09% Sodium azide, may contain carrier protein/stabiliser, ph 7,2.
- Storage temperature:The product should be stored undiluted at 4 °C and should be protected from prolonged exposure to light. Do not freeze.
- Shipping temperature:4 °C
- Purification:The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
- Pk:0,025 mg
The 1D3 monoclonal antibody specifically reacts with mouse CD19, a 95 kDa transmembrane glycoprotein, a member of the Ig superfamily and a B cell-lineage differentiation antigen expressed by all the B lymphocyte development stages, except for the terminally differentiated plasma cells. CD19 associates with CD21, CD81 and MHC class II to form a multi-molecular complex that initiates the mature B lymphocyte activation by interaction with the B-cell receptors. CD 19 enhances the B cell proliferation, development and activation, and the maturation of memory B cells. In CD19-deficient mice, the generation and maturation of B lymphocytes in the bone marrow and periphery are affected.
Type: Primary
Antigen: Cd19
Clonality: Monoclonal
Clone: 1D3
Conjugation: Biotin
Epitope:
Host: Rat
Isotype: IgG2a kappa
Reactivity: Mouse