Specifications
- Antibody type:Primary
- Antigen name:interleukin 2 receptor, alpha chain
- Antigen symbol:Il2ra
- Clonality:Monoclonal
- Clone:PC61.5
- Conjugation:Unconjugated
- Flow cytometry:Yes
- Host:Rat
- ImmunoChemistry:Yes
- ImmunoPrecipitation:Yes
- Isotype:IgG1 lambda
- Reactivity:Mouse
- Cross adsorption:No
- Form:liquid
- Gene ID:P01590
- Antigen synonyms:Il2ra
- Storage buffer:Phosphate-buffered aqueous solution, ≤0,09% Sodium azide, may contain carrier protein/stabiliser, ph 7,2.
- Storage temperature:The product should be stored undiluted at 4 °C and should be protected from prolonged exposure to light. Do not freeze.
- Shipping temperature:4 °C
- Tested applications:Functional
- Purification:The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
- Pk:0,1 mg
Specifications
About this item
The PC61.5 antibody specifically reacts with mouse CD25, the 55 kDa low-affinity Interleukin-2 Receptor alpha chain (IL-2R alpha), expressed on early progenitors of T and B lineage, and on B and T cells. Together with CD122 (IL-2 Receptor beta) and CD 132 (IL-2 Receptor gamma c, the common gamma chain), CD25 forms high-affinity receptor complexes for IL-2. Resting B and T cells and natural killer cells do not express IL-2R alpha. Cd25 is also expressed on the dendritic cells, and it enhances lymphocyte differentiation and activation.The PC61.5 antibody block the binding of IL-2 to both high-affinity and low-affinity receptors.
Type: Primary
Antigen: Il2ra
Clonality: Monoclonal
Clone: PC61.5
Conjugation: Unconjugated
Epitope:
Host: Rat
Isotype: IgG1 lambda
Reactivity: Mouse