- Antibody type:Primary
- Antigen name:Ku-80
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 680
- Host:Rabbit
- Isotype:IgG
- Reactivity:Other
- Western blot:Yes
- Environmentally Preferable:
- Epitope:301-450/732
- Form:Liquid
- Gene ID:7520
- Antigen synonyms:NFIV|KUB2|Ku86|KARP1|KARP-1|CTC85|TLAA|XRCC5|FLJ39089|CTCBF|EC 3.6.1.|KU80|Ku80|G22P2
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:83 kDa
- Storage temperature:Store at –20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human Ku-80
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
Type: Primary
Antigen: Ku-80
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 301-450/732
Host: Rabbit
Isotype: IgG
Reactivity: Others