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Anti-AMPK beta 1 + 2 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Anti-AMPK beta 1 + 2 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Catalog # BOSSBS-3967R-A750
Supplier:  Bioss
Anti-AMPK beta 1 + 2 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Catalog # BOSSBS-3967R-A750
Supplier:  Bioss

Specifications

  • Antibody type:
    Primary
  • Antigen name:
    AMPK beta 1 + 2
  • Clonality:
    Polyclonal
  • Conjugation:
    Alexa Fluor® 750
  • Host:
    Rabbit
  • ImmunoChemistry:
    Yes
  • ImmunoFluorescence:
    Yes
  • Isotype:
    IgG
  • Reactivity:
    Human
  • Environmentally Preferable:
  • Epitope:
    201-272/272
  • Form:
    Liquid
  • Gene ID:
    5565, 5564
  • Antigen synonyms:
    Protein kinase AMP activated beta 2 non catalytic subunit|PRKAB 2|AMPK subunit beta-1|AMPK beta 2 chain|AMPK beta 2|AMP activated protein kinase beta 2 non catalytic subunit|PRKAB1|AMPKb
  • Modification:
    Unmodified
  • Storage buffer:
    Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
  • Molecular weight:
    30 kDa
  • Storage temperature:
    Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
  • Concentration:
    1 µg/µl
  • Shipping temperature:
    4 °C
  • Immunogen:
    KLH conjugated synthetic peptide derived from human AMPK beta 2
  • Tested applications:
    ICC
  • Purification:
    Purified by Protein A
  • Pack type:
    Vial
  • Pk:
    100 µl

Specifications

About this item

PRKAB2 ans PRKAB1 are regulatory subunits of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status and plays a role in protecting cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. AMPK is responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase (ACC). It also regulates cholesterol synthesis via phosphorylation and inactivation of hydroxymethylglutaryl-CoA reductase (HMGCR) and hormone-sensitive lipase. PRKAB2 may be a positive regulator of AMPK activity.

Type: Primary
Antigen: AMPK beta 1 + 2
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 201-272/272
Host: Rabbit
Isotype: IgG
Reactivity: Human