Specifications
- Antibody type:Primary
- Antigen name:CYP21
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 680
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Rat
- Epitope:101-200/494
- Form:Liquid
- Gene ID:1589
- Antigen synonyms:Oh21-1|MGC150536|CPS1|CHOLESTEROL 21-HYDROXYLASE|21OHA|21-OH|MGC150537|CYP21OH-A|CA21H|MGC156449|Cyp21a1|CYP21A2|Oh21-2|21OHB|Cytochrome P450 21|Cyp21a2-ps|P450C21|CAH1|Cyp21-ps1|CP21A_HUMAN|CYP21B|cytochrome P450, family 21, subfamily A, polypeptide 2|CYP21|P450c21B
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:54 kDa
- Storage temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human CYP21
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
Specifications
About this item
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyse many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localises to the endoplasmic reticulum and hydroxylates steroids at the 21 position. Its activity is required for the synthesis of steroid hormones including cortisol and aldosterone. Mutations in this gene cause congenital adrenal hyperplasia. A related pseudogene is located near this gene; gene conversion events involving the functional gene and the pseudogene are thought to account for many cases of steroid 21-hydroxylase deficiency. Two transcript variants encoding different isoforms have been found for this gene.
Type: Primary
Antigen: CYP21
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 101-200/494
Host: Rabbit
Isotype: IgG
Reactivity: Rat