Specifications
- Antibody type:Primary
- Antigen name:DNA Polymerase lambda
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 680
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Rat
- Western blot:Yes
- Epitope:475-575/575
- Form:Liquid
- Gene ID:27343
- Antigen synonyms:Pol Lambda|DNA directed DNA polymerase lambda|OTTHUMP00000020323|EC 2.7.7.7,EC 4.2.99.|BETAN|DNA polymerase beta 2|POLL|DNA polymerase beta-2|DPOLL_HUMAN|DNA polymerase kappa|POL KAPPA|POLKAPPA|DNA polymerase lambda|DNA polymerase lamda2|OTTHUMP00000059179|OTTHUMP00000020321|Pol beta2|FLJ46002|BETA N|DNA polymerase kappa DNA polymerase beta N|Polymerase DNA directed lambda
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol.
- Molecular weight:63 kDa
- Storage temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human DNA Polymerase lambda
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
Specifications
About this item
DNA polymerase lambda (pol lambda), also designated DNA polymerase lambda or Pol Beta2, is a low-fidelity polymerase which plays a role in both spontaneous and DNA damage-induced mutagenesis. Encoded by the POLL gene, pol lambda is a member of the DNA polymerase type-X family. Pol lambda extends primer-terminal mispairs opposite nondamaged DNA templates, suggesting that it may assist in extending mismatched base pairs during normal DNA replication. In addition, pol ?may play a role in the mutagenic bypass of T-T dimers. Proliferating cell nuclear antigen (PCNA), a protein essential to DNA replication, interacts with pol lambda and thus influences the ability of pol ?to synthesize DNA.
Type: Primary
Antigen: DNA Polymerase lambda
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 475-575/575
Host: Rabbit
Isotype: IgG
Reactivity: Rat