Anti-DNA polymerase eta Rabbit Polyclonal Antibody (Alexa Fluor® 680)
BOSSBS-13016R-A680
: Bioss
- Antibody type:Primary
- Antigen name:DNA polymerase eta
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 680
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Western blot:Yes
- Epitope:51-160/713
- Form:Liquid
- Gene ID:5429
- Antigen synonyms:XP V|POLH_HUMAN|RAD30A|RAD30|polymerase DNA directed eta|FLJ16395|DNA polymerase eta|POLH|FLJ21978|XPV|RAD30 homolog A|Xeroderma pigmentosum variant type protein
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol.
- Molecular weight:78 kDa
- Storage temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human DNA polymerase eta
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Plays an important role in the repair of UV-induced pyrimidine dimers. Depending on the context, it inserts the correct base, but causes frequent base transitions and transversions. May play a role in hypermutation at immunoglobulin genes. Forms a Schiff base with 5'-deoxyribose phosphate at abasic sites, but does not have lyase activity. Targets POLI to replication foci.
Type: Primary
Antigen: DNA polymerase eta
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 51-160/713
Host: Rabbit
Isotype: IgG
Reactivity: