An Sandwich ELISA kit for quantifying human amyloid beta 42 alpha in biological fluids.

• Easy, convenient and time-saving method to measure the level of Amyloid beta 24 alpha in human serum, plasma, tissue homogenates, culture supernatants and other biological fluids
• Detection Range: 15,62 to 1000 pg/ml
• Sensitivity: <9,375 pg/ml
• Assay Precision: Intra-Assay: CV <8%; Inter-Assay: CV <10%

Amyloid beta (Aβ or Abeta) denotes peptides of 36 to 43 amino acids that are crucially involved in Alzheimer's disease as the main component of the amyloid plaques found in the brains of Alzheimer patients. The peptides result from the amyloid precursor protein (APP), which is cleaved by beta secretase and gamma secretase to yield Aβ. Aβ molecules can aggregate to form flexible soluble oligomers which may exist in several forms. It is now believed that certain misfolded oligomers (known as ''seeds'') can induce other Aβ molecules to also take the misfolded oligomeric form, leading to a chain reaction akin to a prion infection. The seeds or the resulting amyloid plaques are toxic to nerve cells.

The other protein implicated in Alzheimer's disease, tau protein, also forms such prion-like misfolded oligomers, and there is some evidence that misfolded Aβ can induce tau to misfold. BioVision’s Amyloid Beta 42 ELISA kit is a sandwich ELISA assay for the quantitative measurement of human Amyloid Beta 42 in serum, plasma and cell culture supernatants. The density of color is proportional to the amount of human Amyloid Beta 42 captured from the samples.

All products are FOR RESEARCH USE ONLY.   PRODUCTS ARE NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES.  Customer is granted a limited use non-exclusive licence for its own internal research.  Any control manufacturer supplies with a Product is limited to use only to validate the relevant Product.  By using the Product, Customers agree not to attempt to reverse engineer or otherwise perform any compositional, structural, functional or other analyses directed to learning the methodology, formulae, sequences, processes, make-up or production of any of the Products or portions thereof.