These Avantor® Hichrom C18 columns offer high performance in order to tackle the most challenging reversed-phase applications. The use of ultra pure silica, advanced bonding technology, superior column specification and comprehensive batch validation all contribute to the columns’ excellent reproducibility.

• Ultra pure, base deactivated porous silica
• Suitable for acidic, basic and neutral molecules
• Particle sizes 3,5 and 5 μm available

Combining ultra pure silica with advanced bonding technology results in a densely bonded silica that is both highly robust and highly reproducible. Unpredictable interactions between residual silanol sites on the silica surface and the analyte are effectively eliminated. Comprehensive batch validation ensures absolute batch to batch reproducibility is maintained with acidic, basic and neutral molecules.

Combining a unique dense bonding process (inhibiting ligand cleavage at low pH) with a revolutionary capping process (shielding the silica from dissolution at high pH) enables these C18 columns to offer exceptional stability across an extended pH range.

These columns are packed to extremely high efficiencies with excellent peak asymmetries, ensuring that high performance is maintained throughout the column’s lifetime.

Guard cartridges are available for C18 column dimensions, to further extend column lifetime by preventing irreversible adsorption and frit blockage at the top of the column.

* Use with freestanding holder HI-161 and column coupler HI-081.