Human Recombinant IL-11 (from E. coli)

Supplier: Shenandoah Biotechnology

Certificates

Supplier: Shenandoah Biotechnology

About this item

Interleukin 11 (IL-11) is a member of the gp130 family of cytokines. IL-11 functions to promote hematopoietic stem cell proliferation and megakaryocyte differentiation. In non-hematopoietic cell populations, IL-11 stimulates acute-phase proteins, modulates the development of immunoglobulin-producing B cells, and regulates bone turnover. IL-11 binds the IL-11Rα receptor to activate JAK downstream signaling. Human IL-11 shows activity on murine cells.

High quality
Low endotoxin
Affordable

Shenandoah Biotechnology is a manufacturer of research grade recombinant proteins typically used as cytokines, growth factors and chemokines in cell based assays and cell culture. Each production lot is tested for QA and the expected values for each product can be viewed under the product specifications tab.

Delivery: A certificate of analysis (COA) is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.

Caution: For research use only.

Specifications

Conjugation:
Unconjugated
Protein function:
Cytokine
Protein/peptide type:
Recombinant
Source:
E. coli
Species:
Human
Storage conditions:
−20 °C
Endotoxin content:
Endotoxin LAL (EU/µg) ≤0.1
Biological activity:
Bioactivity assay: TF-1 Cell Proliferation, ED50 ≤10 ng/ml, bioactivity ≥1,0×10⁵ units/mg
Gene ID:
P20809
Reconstitution instructions:
Sterile water at 0,1 mg/ml
Endotoxin-free:
N
Carrier-free:
Y
Protease-free:
N
Animal-free:
N
Protein synonyms:
oprelvekin|AGIF (Adipogenesis Inhibitory Factor)
UniProtKB:
P20809
Protein/peptide name:
IL-11
Purity:
≥95%
Molecular weight:
19,3 kDa
Sequence:
MPGPPPGPPR VSPDPRAELD STVLLTRSLL ADTRQLAAQL RDKFPADGDH NLDSLPTLAM SAGALGALQL PGVLTRLRAD LLSYLRHVQW LRRAGGSSLK TLEPELGTLQ ARLDRLLRRL QLLMSRLALP QPPPDPPAPP LAPPSSAWGG IRAAHAILGG LHLTLDWAVR GLLLLKTRL
Endotoxin level:
Low
Formulation:
0,1% Trifluoroacetic Acid (TFA)
Nuclease-free:
N
Grade:
RUO
Shipping temperature:
RT
Tested applications:
Bioassay