Mouse recombinant CD54 non-lytic (from CHO cells)
PRSI90-397
:
- Pk:50 µG
- Protein/peptide type:Recombinant
- Source:CHO cells
- Species:Mouse
- Tag sequence:Fc Tag
- Storage conditions:Stable for at least 1 year after receipt when stored at −20 °C. Working aliquots are stable for up to 3 months when stored at −20 °C.
- Biological activity:Shows the biological function of the CD54 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain.
- Protein synonyms:Intercellular Adhesion Molecule 1|ICAM1
- Protein/peptide name:CD54 non-lytic
- Purity:>98% (SDS-PAGE)
- Sequence:28-485
- Formulation:Lyophilized from 0.2um-filtered solution in PBS.
Intercellular Adhesion Molecule-1 (ICAM-1, CD54) binds the leukocyte integrins LFA-1 and Mac1. CD54 expression is weak on leukocytes, epithelial and resting endothelial cells, as well as some other cell types, but expression can be stimulated by IFN-gamma, TNF-alpha, IL-1beta and LPS. Soluble CD54 is found in a biologically active form in serum, probably as a result of proteolytic cleavage from the cell surface, and is elevated in patients with various inflammatory syndromes such as septic shock, LAD, cancer and transplantation.
- This recombinant proteins is for research use only.
Fusion-Tag: Fc Tag
This recombinant proteins is for research use only.