The proprietary derivatisation procedure for YMCbasic produces a material with controlled surface coverage, which gives excellent lot-to-lot reproducibility. Used as an alternative bonding approach to reduce peak tailing of basic pharmaceuticals.

• No need for ion pair reagents or amine modifiers
• Complementing selectivity to C8 and C18 materials
• High resolution and excellent peak symmetry for basic compound

YMCbasic is suitable for separation of acidic compounds, showing slight retention of highly polar acid compounds such as maleate. This provides a complementing selectivity with conventional C8 and C18 materials, but without peak tailing for basic compounds.