UACA (Uveal Autoantigen with Coiled-coil domains and Ankyrin repeats) is a 1,416 amino acid nuclear membrane protein. It was originally identified as an autoantigen in patients with panuveitis, a characteristic of Vogt-Koyanagi-Harada disease, and in patients with Graves' disease. UACA was also later identified as Nucling, an mRNA differentially expressed in F9 embryonal carcinoma cells during cardiac muscle differentiation. UACA appears to function as a pro-apoptotic protein that recruits the apaf-1-pro-caspase-9 complex for the induction of apoptosis to mediate the cell-death pathway.
Type: Primary
Antigen: UACA
Clonality: Monoclonal
Clone: UACA/1222
Conjugation: CF568
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human, Mouse
- Catalog No:
- BNC681222-500
- BNC681222-100
- Antigen symbol:
- UACA
- UACA
- Antigen name:
- UACA / Nucling
- UACA / Nucling
- Antigen synonyms:
- Uveal autoantigen with coiled-coil domains and ankyrin repeats (UACA)|NUCLING|Nuclear membrane binding protein
- Uveal autoantigen with coiled-coil domains and ankyrin repeats (UACA)|NUCLING|Nuclear membrane binding protein
- Antibody type:
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Conjugation:
- CF® 568
- CF® 568
- Clone:
- Clone UACA/1222
- Clone UACA/1222
- Reactivity:
- Human, Mouse
- Human, Mouse
- Host:
- Mouse
- Mouse
- Gene ID:
- 108049
- 108049
- Isotype:
- IgG1 kappa
- IgG1 kappa
- Western blot:
- Yes
- Yes
- ImmunoFluorescence:
- Yes
- Yes
- Concentration:
- 0,1 mg/ml
- 0,1 mg/ml
- Storage buffer:
- PBS/0,1% BSA/0,05% azide
- PBS/0,1% BSA/0,05% azide
: VWR Chemicals
: VWR Collection
: KIMBERLY CLARK
: VWR Collection
: VWR Collection
: VWR Chemicals
: VWR Collection
: VWR Collection