About this item
The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2 -independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease.
Type: Primary
Antigen: MCAM
Clonality: Monoclonal
Clone: MUC18/1130
Conjugation: CF405S
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human
Specifications
- Catalog No:
- BNC041130-100
- BNC041130-500
- Antigen symbol:
- MCAM
- MCAM
- Antigen name:
- MUC18 / Mucin 18 / CD146
- MUC18 / Mucin 18 / CD146
- Antibody type:
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Conjugation:
- CF® 405S
- CF® 405S
- Clone:
- Clone MUC18/1130
- Clone MUC18/1130
- Reactivity:
- Human
- Human
- Host:
- Mouse
- Mouse
- Gene ID:
- 599039
- 599039
- Isotype:
- IgG1 kappa
- IgG1 kappa
- ImmunoChemistry:
- Yes
- Yes
- ImmunoFluorescence:
- Yes
- Yes
- Concentration:
- 0,1 mg/ml
- 0,1 mg/ml
- Storage buffer:
- PBS/0,1% BSA/0,05% azide
- PBS/0,1% BSA/0,05% azide
Specifications
Supplier: HEATHROW
Supplier: VWR Chemicals
Supplier: VWR Collection
Supplier: VWR Collection
Supplier: VWR Chemicals
Supplier: VWR Chemicals
Supplier: VWR Collection
Supplier: KIMBERLY CLARK
Supplier: VWR Collection
Supplier: VWR Chemicals
Supplier: VWR Collection
Supplier: Merck