About this item
Recognizes a protein of 110 kDa, which is identified as androgen receptor (AR). It reacts with full length, and the newly described A form of the receptor. It does not cross react with estrogen, progesterone, or glucocorticoid receptors. The expression of AR is reportedly inversely correlated with histologic grade i.e. well differentiated prostate tumors show higher expression than the poorly differentiated tumors. In prostate cancer, AR has been proposed, as a marker of hormone-responsiveness and thus it may be useful in identifying patients likely to benefit from anti-androgen therapy. Anti-androgen receptor has been useful clinically in differentiating morpheaform basal cell carcinoma (mBCC) from desmoplastic trichoepithelioma (DTE) in the skin.This MAb is superb for staining of formalin/paraffin tissues.
Type: Primary
Antigen: AR
Clonality: Monoclonal
Clone: AR441
Conjugation: CF647
Epitope:
Host: Mouse
Reactivity: Human
Isotype: IgG1, kappa
Specifications
- Catalog No:
- BNC470881-100
- BNC470881-500
- Antigen symbol:
- AR
- AR
- Antigen name:
- Androgen Receptor
- Androgen Receptor
- Antibody type:
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Conjugation:
- CF® 647
- CF® 647
- Clone:
- Clone AR441
- Clone AR441
- Reactivity:
- Human
- Human
- Host:
- Mouse
- Mouse
- Gene ID:
- 496240
- 496240
- Isotype:
- IgG1 kappa
- IgG1 kappa
- ImmunoChemistry:
- Yes
- Yes
- ImmunoFluorescence:
- Yes
- Yes
- Concentration:
- 0,1 mg/ml
- 0,1 mg/ml
- Storage buffer:
- PBS/0,1% BSA/0,05% azide
- PBS/0,1% BSA/0,05% azide