Pierce™ Thiophilic adsorbent is a protein-free immunosorbent resin for gentle preferential binding and purification of immunoglobulins from a variety of sources including mouse, rat, rabbit, goat and human. This Pierce™ Thiophilic Adsorption Kit is a purification kit containing columns pre-packed with the resin and ready-to-use buffers.

• High capacity - gently binds and purifies
• Broad antibody specificity
• Simple and fast - quickly fractionate and purify the immunoglobulin component
• Binding condition is non denaturing and the elution buffer yields concentrated, salt-free immunoglobulin

Thiophilic adsorption is based on the ability of some proteins, particularly immunoglobulins, to bind to an immobilised ligand that contains a sulfone group in close proximity to a thioether. Salts that interact with water molecules, such as potassium and ammonium sulfate, promote this binding by driving the protein into close proximity with the ligand.