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MK-571 sodium salt ≥90% (by HPLC)
Supplier: Enzo Life Sciences
A potent, selective, orally active leukotriene D₄ antagonist. Ki=2.1 nM for inhibition of [³H]-LTD₄ binding to human lung membranes. Competitively antagonizes contractions of guinea pig trachea and ileum and human trachea induced by LTD₄. Blocks LTD₄ and ascaris-induced bronchoconstriction in conscious squirrel monkeys.
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