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Anti-DHRS2 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Anti-DHRS2 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Catalog # BOSSBS-8573R-A750
Supplier:  Bioss
Anti-DHRS2 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Catalog # BOSSBS-8573R-A750
Supplier:  Bioss

Specifications

  • Antibody type:
    Primary
  • Antigen name:
    DHRS2
  • Clonality:
    Polyclonal
  • Conjugation:
    Alexa Fluor® 750
  • Host:
    Rabbit
  • ImmunoChemistry:
    Yes
  • ImmunoFluorescence:
    Yes
  • Isotype:
    IgG
  • Reactivity:
    Human,
    Rat
  • Western blot:
    Yes
  • Epitope:
    21-120/258
  • Form:
    Liquid
  • Gene ID:
    10202
  • Antigen synonyms:
    SDR25C1|Dehydrogenase/reductase SDR family member 2, mitochondrial|HEP27|DHRS2|Protein D|Dicarbonyl reductase HEP27
  • Modification:
    Unmodified
  • Storage buffer:
    Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
  • Molecular weight:
    27 kDa
  • Storage temperature:
    Store at ‒20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
  • Concentration:
    1 µg/µl
  • Shipping temperature:
    4 °C
  • Immunogen:
    KLH conjugated synthetic peptide derived from human DHRS2
  • Tested applications:
    ICC
  • Purification:
    Purified by Protein A
  • Pack type:
    Vial
  • Pk:
    100 µl

Specifications

About this item

Displays NADPH-dependent dicarbonyl reductase activity in vitro with 3,4-Hexanedione, 2,3-Heptanedione and 1-Phenyl-1,2-propanedione as substrates. No reductase activity is displayed in vitro with steroids, retinoids and sugars as substrates. Attenuates MDM2-mediated p53/TP53 degradation, leading to p53/TP53 stabilisation and increased transcription activity, resulting in the accumulation of MDM2 and CDKN1A/p21.

Type: Primary
Antigen: DHRS2
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 21-120/258
Host: Rabbit
Isotype: IgG
Reactivity: Human; Rat

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