"vac1&"
Anti-KCNQ1 Rabbit Polyclonal Antibody (Alexa Fluor® 350)
Supplier: BIOSS INC
Probably important in cardiac repolarization. Associates with KCNE1 (MinK) to form the I(Ks) cardiac potassium current. Elicits a rapidly activating, potassium-selective outward current. Muscarinic agonist oxotremorine-M strongly suppresses KCNQ1/KCNE1 current in CHO cells in which cloned KCNQ1/KCNE1 channels were coexpressed with M1 muscarinic receptors. May associate also with KCNE3 (MiRP2) to form the potassium channel that is important for cyclic AMP-stimulated intestinal secretion of chloride ions, which is reduced in cystic fibrosis and pathologically stimulated in cholera and other forms of secretory diarrhea.
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Anti-NUAK2 Mouse Monoclonal Antibody [clone: 2F9]
Supplier: UNITED STATES BIOLOGICAL
Anti-NUAK2 Mouse Monoclonal Antibody [clone: 2F9]
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Anti-CAMP Rabbit Polyclonal Antibody
Supplier: BIORBYT
Anti-CAMP Rabbit Polyclonal Antibody
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Anti-GPR31 Rabbit Polyclonal Antibody
Supplier: BIOSS INC
G protein-coupled receptors (GPCRs), also designated seven transmembrane (7TM) receptors and heptahelical receptors, are a protein family which interacts with G proteins (heterotrimeric GTPases) to synthesize intracellular second messengers such as diacylglycerol, cyclic AMP, inositol phosphates and calcium ions. Their diverse biological functions range from vision and olfaction to neuronal and endocrine signaling, along with involvement in many pathological conditions. GPR31 (G-protein coupled receptor 31) is a 319 amino acid orphan receptor that localizes to the cell membrane. GPR31 shares 25-33% homology with members of the chemokine, purino and somatostatin receptor gene families.
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Anti-CACNG7 Rabbit Polyclonal Antibody
Supplier: UNITED STATES BIOLOGICAL
Anti-CACNG7 Rabbit Polyclonal Antibody
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Anti-GRM6 Rabbit Polyclonal Antibody
Supplier: PROSCI
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. GRM6 is part of Group III which is linked to the inhibition of the cyclic AMP cascade.
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Anti-CACNG7 Mouse Monoclonal Antibody [clone: 1F7]
Supplier: UNITED STATES BIOLOGICAL
Anti-CACNG7 Mouse Monoclonal Antibody [clone: 1F7]
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Anti-NUDT10 Rabbit Polyclonal Antibody
Supplier: UNITED STATES BIOLOGICAL
Anti-NUDT10 Rabbit Polyclonal Antibody
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Anti-G protein alpha Rabbit Polyclonal Antibody
Supplier: BIOSS INC
GTP-binding proteins (G-proteins)are a family of heterotrimeric proteins that play a critical role in signal transduction by coupling cell surface, 7-transmembrane domain receptors to intracellular signaling pathways including second messenger generation (such as cyclic AMP, calcium and diacylglycerol), protein phosphorylation, ion channel activation, gene induction, cell growth and differentiation. Receptor activation catalyzes the exchange of GTP for GDP bound to the inactive G protein alpha subunit resulting in a conformational change and dissociation of the complex. The G protein alpha and beta-gamma subunits are capable of regulating various cellular effectors. Activation is terminated by a GTPase intrinsic to the G-alpha subunit.
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Anti-CCNM3 Rabbit Polyclonal Antibody
Supplier: BIOSS INC
Cyclin M3 is a 707 amino acid multi-pass membrane protein that shares weak sequence similarity with cyclin proteins, yet displays no cyclin-like function in vivo. Though ubiquitously expressed, Cyclin M3 is found at highest levels in kidney, brain, spleen and heart. Cyclin M3 is localized to the nucleus where it is likely a metal transporter. Cyclin M3 contains two CBS domains, which appear to bind ligands with an adenosyl group such as AMP, ATP and S-AdoMet and may play a regulatory role in sensitizing proteins to adenosyl-carrying ligands. There are three isoforms of Cyclin M3 that are produced as a result of alternative splicing events.
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Anti-NUDT10 Rabbit Polyclonal Antibody (Biotin)
Supplier: UNITED STATES BIOLOGICAL
Anti-NUDT10 Rabbit Polyclonal Antibody (Biotin)
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Anti-CACNG3 Mouse Monoclonal Antibody [clone: 3E4]
Supplier: UNITED STATES BIOLOGICAL
Anti-CACNG3 Mouse Monoclonal Antibody [clone: 3E4]
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Anti-ATF7 Goat Polyclonal Antibody
Supplier: UNITED STATES BIOLOGICAL
Anti-ATF7 Goat Polyclonal Antibody
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Anti-ENTPD5 Rabbit Polyclonal Antibody (Cy7®)
Supplier: BIOSS INC
Uridine diphosphatase (UDPase) that promotes protein N-glycosylation and ATP level regulation. UDP hydrolysis promotes protein N-glycosylation and folding in the endoplasmic reticulum, as well as elevated ATP consumption in the cytosol via an ATP hydrolysis cycle. Together with CMPK1 and AK1, constitutes an ATP hydrolysis cycle that converts ATP to AMP and results in a compensatory increase in aerobic glycolysis. The nucleotide hydrolyzing preference is GDP >IDP >UDP, but not any other nucleoside di-, mono- or triphosphates, nor thiamine pyrophosphate. Plays a key role in the AKT1-PTEN signaling pathway by promoting glycolysis in proliferating cells in response to phosphoinositide 3-kinase (PI3K) signaling.
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Anti-ENTPD5 Rabbit Polyclonal Antibody (Cy3®)
Supplier: BIOSS INC
Uridine diphosphatase (UDPase) that promotes protein N-glycosylation and ATP level regulation. UDP hydrolysis promotes protein N-glycosylation and folding in the endoplasmic reticulum, as well as elevated ATP consumption in the cytosol via an ATP hydrolysis cycle. Together with CMPK1 and AK1, constitutes an ATP hydrolysis cycle that converts ATP to AMP and results in a compensatory increase in aerobic glycolysis. The nucleotide hydrolyzing preference is GDP >IDP >UDP, but not any other nucleoside di-, mono- or triphosphates, nor thiamine pyrophosphate. Plays a key role in the AKT1-PTEN signaling pathway by promoting glycolysis in proliferating cells in response to phosphoinositide 3-kinase (PI3K) signaling.
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Anti-GNAT1 Rabbit Polyclonal Antibody (Cy3®)
Supplier: BIOSS INC
GTP-binding proteins (G-proteins)are a family of heterotrimeric proteins that play a critical role in signal transduction by coupling cell surface, 7-transmembrane domain receptors to intracellular signaling pathways including second messenger generation (such as cyclic AMP, calcium and diacylglycerol), protein phosphorylation, ion channel activation, gene induction, cell growth and differentiation. Receptor activation catalyzes the exchange of GTP for GDP bound to the inactive G protein alpha subunit resulting in a conformational change and dissociation of the complex. The G protein alpha and beta-gamma subunits are capable of regulating various cellular effectors. Activation is terminated by a GTPase intrinsic to the G-alpha subunit.



