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5268 Results for: "ENZO LIFE SCIENCES"

Congo red ≥95% (by HPLC), Ultrapure

Supplier: ENZO LIFE SCIENCES

beta-Amyloid dye

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RSSR ≥97% (by HPLC), crystalline powder

RSSR ≥97% (by HPLC), crystalline powder

Supplier: ENZO LIFE SCIENCES

Supersensitive spin label

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TMH hydrochloride

TMH hydrochloride

Supplier: ENZO LIFE SCIENCES

Cyclic hydroxylamine spin probe for in vivo, intraperitoneal and intravenous injections.

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Corning Life Sciences

Why Choose Corning Fetal Bovine Serum?

Our vertically integrated FBS serum supply chain, from collection to scientist, allows us to provide a consistent supply of FBS.

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4-Phenylchalcone oxide (synthetic) ≥98% (by HPLC)

Supplier: ENZO LIFE SCIENCES

Potent and selective inhibitor of microsomal and cytosolic epoxide hydrolase (IC50=68 nM). Inhibits epoxide hydrolysis of epoxyeicosatrienoic acids.

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Olomoucine ≥98%, high purity

Supplier: ENZO LIFE SCIENCES

Olomoucine is a purine derivative which acts as a potent and selective inhibitor of CDK1 (p34cdc2)/cyclin B and related kinases. It acts by competing for the ATP binding domain of the kinase. Of 35 protein kinases tested, olomoucine inhibited p33CDK2/cyclin A, p33CDK2/cyclin E, p34cdc2/cyclin B, p33CDK5/p35 and erk1 with IC50 of 7, 7, 7, 3 and 25µM respectively. The related kinases p34CDK4/cyclin D and p40CDK6/cyclin D3 were not inhibited or were less sensitive to olomoucine, IC50 > 1000 and 250µM respectively. PKC, PKA, PKG, CaM kinase II, MLC kinase, CK2, EGFR tyrosine kinase, p56lck, p56lyn, p60c-src, v-abl and insulin receptor tyrosine kinase are not inhibited or are weakly inhibited at 1mM. It delays mouse oocyte maturation and inhibits the growth of a variety of human cell lines including Rhabdomyosarcoma cell line Rh1, Rh18, Rh28 and Rh30; MCF-7, KB-3-1 and their adriamycin-resistant counterparts (IC50=18-86µM). It inhibits DNA synthesis in interleukin-2-stimulated T lymphocytes and triggers a G1 arrest similar to interleukin-2 deprivation. Can be used to synchronize cells in G1. Triggers apoptosis in target tumor cells in vitro and in vivo and in maturing cerebellar granule neurons. N9-Isopropyl-olomoucine and the negative control Iso-olomoucine are also available.

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Pifithrin-mu ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES

HSP70 inhibitor

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Z-DEVD-pNA

Supplier: ENZO LIFE SCIENCES

Caspase substrate

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Oxamflatin ≥95% (by HPLC)

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HDAC inhibitor

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Geranylgeranylpyrophosphate triammonium salt 1mg/ml ≥98%

Geranylgeranylpyrophosphate triammonium salt 1mg/ml ≥98%

Supplier: ENZO LIFE SCIENCES

Geranylgeranyl-donor.

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Prostaglandin D₂ ≥98% (by HPLC)

Prostaglandin D₂ ≥98% (by HPLC)

Supplier: ENZO LIFE SCIENCES

Prostanoid receptor ligand.

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TRAM 34 ≥98% (by HPLC)

Supplier: ENZO LIFE SCIENCES

TRAM-34 is a potent and selective inhibitor of the intermediate-conductance Ca2+-activated potassium channel (IKCa). It displays immunosuppressive activity and inhibits the proliferation of endometrial cancer cells.

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(+)-Himbacine ≥98%, powder

(+)-Himbacine ≥98%, powder

Supplier: ENZO LIFE SCIENCES

Muscarinic acetylcholine receptor antagonist.

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Spermine tetrahydrochloride

Supplier: ENZO LIFE SCIENCES

Spermine tetrahydrochloride

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TMTH hydrochloride ≥99%

TMTH hydrochloride ≥99%

Supplier: ENZO LIFE SCIENCES

Cyclic hydroxylamine spin probe for in vivo, intraperitoneal and intravenous injections.

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1-Acetoxy-3-carbamoyl-2,2,5,5-tetramethylpyrrolidine (ACP)

1-Acetoxy-3-carbamoyl-2,2,5,5-tetramethylpyrrolidine (ACP)

Supplier: ENZO LIFE SCIENCES

Cell permeable probe for the detection of intracellular oxidative stress.

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Irinotecan hydrochloride trihydrate ≥98% (by HPLC)

Supplier: ENZO LIFE SCIENCES

Topoisomerase I inhibitor

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Undeca-ubiquitin (linear)

Supplier: ENZO LIFE SCIENCES

Produced in E. coli.

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N-ω-Propyl-L-arginine ≥98%

Supplier: ENZO LIFE SCIENCES

nNOS inhibitor

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LFM-A13 ≥97%

Supplier: ENZO LIFE SCIENCES

BTK inhibitor

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IL-4 (mouse), ELISA kit

Supplier: ENZO LIFE SCIENCES

For the quantitative determination of mouse IL-4 in culture supernatants and serum. Cited sample type includes plasma.

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Gastrin I (human), ELISA kit

Supplier: ENZO LIFE SCIENCES

For the quantitative determination of human Gastrin I in culture supernatants, plasma, and serum.

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Extraction reagents

Supplier: ENZO LIFE SCIENCES

Concentrated lysis buffer for preparation of cell and tissue extracts.

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Leptin (human), ELISA kit

Supplier: ENZO LIFE SCIENCES

For the quantitative determination of human leptin in culture supernatants, plasma, and serum.

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cGMP ELISA kit

Supplier: ENZO LIFE SCIENCES

Most sensitive (0,088pmol/m) colorimetric kit for extracellular cGMP quantification.

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Fixation/Permeabilisation, (buffer)

Supplier: ENZO LIFE SCIENCES

Fixation/Permeabilization, (buffer)

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PGE2 FPIA kit

Supplier: ENZO LIFE SCIENCES

For the quantitative determination of PGE2 in culture supernatants from any species.

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PGE2 high sensitivity ELISA kit, plasma

Supplier: ENZO LIFE SCIENCES

Ultrasensitive PGE2 ELISA kit for inflammation and eicosanoid research.

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Human recombinant TNF alpha (1) (from E. coli)

Supplier: ENZO LIFE SCIENCES

Produced in E.coli.

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Chemiluminescent acridinium esters

Chemiluminescent acridinium esters

Supplier: ENZO LIFE SCIENCES

Chemiluminescent acridinium esters are commonly used to label antibodies, proteins, nucleic acids, and some peptides, and are frequently used as detection reagents in immunoassays.

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Anti-CD40 Rabbit Polyclonal Antibody

Supplier: ENZO LIFE SCIENCES

CD40 is a 45-50 kDa type I membrane protein and a member of the tumor necrosis factor (TNF) receptor superfamily. CD40 is also known as pb50 or CDW40.  CD40 is expressed primarily by professional antigen-presenting cells and it is also expressed on non-immune cell types. The CD40 expressed by professional antigen-presenting cells plays a critical role in co-stimulation and antigen-presenting cell activation in T cell-dependent immune responses. Signals generated through CD40 in B cells are anti-apoptotic. These signals are also required for T cell-dependent B cell activation and proliferation, isotype switching, up-regulation of costimulatory receptors, germinal center formation and memory generation. CD40 signal transduction is initiated by binding trimeric CD40 ligand (CD40L) which is found on the surface of activated T cells.  CD40 engages several signalling pathways in B cells and these include NF-kB, the mitogen-activated protein kinases p38 and c-Jun N-terminal kinase. The 62 amino acid cytoplasmic domain (CD40c) of CD40 contains two linear TNF-receptor associated factor (TRAF) binding domains. The membrane proximal site of CD40c binds TRAF6 and the membrane distal site binds TRAF1, 2 and 3. CD40c is thought to mediate the CD40-dependant signalling pathways by recruitment of TRAF to this multimerized domain. CD40 ligation has also been shown to stimulate iNOS expression, and therefore NO production, by activating NF-kB in IFN-g treated microglial cells. NO derived from microglia has been implicated in the damage of myelin-producing oligodendrocytes in demyelinating disorders like multiple sclerosis (MS) and neuronal death during Alzheimer’s disease and brain trauma. Increased CD40-CD40 ligation has been implicated in the pathogenesis of several autoimmune inflammatory diseases, such as MS, arthritis and insulin-dependant diabetes.

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