51458 Results for: "CAYMAN"

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An orally bioavailable, ATP-competitive inhibitor of mutant V600E and wild type B-Raf kinases (IC50s = 31 and 100 nM, respectively) 1 * 10 mg

Supplier: CAYMAN

An orally bioavailable, ATP-competitive inhibitor of mutant V600E and wild type B-Raf kinases (IC50s = 31 and 100 nM, respectively) 1 * 10 mg

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A selective autotaxin inhibitor (IC50 = 5.7 nM) that has been shown to dose-dependently block thrombin-induced LPA secretion in plat elets 1 * 25 mg

Supplier: CAYMAN

A selective autotaxin inhibitor (IC50 = 5.7 nM) that has been shown to dose-dependently block thrombin-induced LPA secretion in plat elets 1 * 25 mg

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A specific inhibitor of breast cancer resistance protein (BCRP/ABCG2) multidrug efflux transporter 1 * 1 mg

Supplier: CAYMAN

A specific inhibitor of breast cancer resistance protein (BCRP/ABCG2) multidrug efflux transporter 1 * 1 mg

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ERYTHROMYCIN A ENOL ETHER 1 * 1 mg

Supplier: CAYMAN

ERYTHROMYCIN A ENOL ETHER 1 * 1 mg

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A selective JAK2 inhibitor that blocks signaling (IC50 = 58 nM at 5 mM ATP) and proliferation of JAK2-expressing cell lines (GI50 = 60 nM) 1 * 10 mg

Supplier: CAYMAN

A selective JAK2 inhibitor that blocks signaling (IC50 = 58 nM at 5 mM ATP) and proliferation of JAK2-expressing cell lines (GI50 = 60 nM) 1 * 10 mg

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A selective autotaxin inhibitor (IC50 = 5.7 nM) that has been shown to dose-dependently block thrombin-induced LPA secretion in plat elets 1 * 10 mg

Supplier: CAYMAN

A selective autotaxin inhibitor (IC50 = 5.7 nM) that has been shown to dose-dependently block thrombin-induced LPA secretion in plat elets 1 * 10 mg

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A selective JAK2 inhibitor that blocks signaling (IC50 = 58 nM at 5 mM ATP) and proliferation of JAK2-expressing cell lines (GI50 = 60 nM) 1 * 50 mg

Supplier: CAYMAN

A selective JAK2 inhibitor that blocks signaling (IC50 = 58 nM at 5 mM ATP) and proliferation of JAK2-expressing cell lines (GI50 = 60 nM) 1 * 50 mg

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A selective JAK2 inhibitor that blocks signaling (IC50 = 58 nM at 5 mM ATP) and proliferation of JAK2-expressing cell lines (GI50 = 60 nM) 1 * 5 mg

Supplier: CAYMAN

A selective JAK2 inhibitor that blocks signaling (IC50 = 58 nM at 5 mM ATP) and proliferation of JAK2-expressing cell lines (GI50 = 60 nM) 1 * 5 mg

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ERYTHROMYCIN A ENOL ETHER 1 * 10 mg

Supplier: CAYMAN

ERYTHROMYCIN A ENOL ETHER 1 * 10 mg

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An inhibitor of the DNA methyltransferases DNMT1, DNMT3A, and DNMT3B (IC50s = 12.5, 8, and 7.5 M, respectively, with Poly(dI-dC) as the substrate) 1 * 5 mg

Supplier: CAYMAN

An inhibitor of the DNA methyltransferases DNMT1, DNMT3A, and DNMT3B (IC50s = 12.5, 8, and 7.5 M, respectively, with Poly(dI-dC) as the substrate) 1 * 5 mg

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An inhibitor of the DNA methyltransferases DNMT1, DNMT3A, and DNMT3B (IC50s = 12.5, 8, and 7.5 M, respectively, with Poly(dI-dC) as the substrate) 1 * 1 mg

Supplier: CAYMAN

An inhibitor of the DNA methyltransferases DNMT1, DNMT3A, and DNMT3B (IC50s = 12.5, 8, and 7.5 M, respectively, with Poly(dI-dC) as the substrate) 1 * 1 mg

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An inhibitor of the DNA methyltransferases DNMT1, DNMT3A, and DNMT3B (IC50s = 12.5, 8, and 7.5 M, respectively, with Poly(dI-dC) as the substrate) 1 * 50 mg

Supplier: CAYMAN

An inhibitor of the DNA methyltransferases DNMT1, DNMT3A, and DNMT3B (IC50s = 12.5, 8, and 7.5 M, respectively, with Poly(dI-dC) as the substrate) 1 * 50 mg

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A quinolone antibiotic that inhibits bacterial DNA gyrase, but not eukaryotic topoisomerases, reversibly binding gyrase subunit A in gyrase-DNA complexes , blocking supercoiling activity and inhibiting DNA synthesis at 0.5-5 µg/ml 1 * 10 g

Supplier: CAYMAN

A quinolone antibiotic that inhibits bacterial DNA gyrase, but not eukaryotic topoisomerases, reversibly binding gyrase subunit A in gyrase-DNA complexes , blocking supercoiling activity and inhibiting DNA synthesis at 0.5-5 µg/ml 1 * 10 g

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An activator of Ca2+-sensitive K+ channels (EC50 = 490 µM in T84 human carcinoma cells) 1 * 5 mg

Supplier: CAYMAN

An activator of Ca2+-sensitive K+ channels (EC50 = 490 µM in T84 human carcinoma cells) 1 * 5 mg

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A positive allosteric modulator of the 7 neuronal nAChR, increasing agonist-evoked calcium flux (EC50 = 216 nM) 1 * 5 mg

Supplier: CAYMAN

A positive allosteric modulator of the 7 neuronal nAChR, increasing agonist-evoked calcium flux (EC50 = 216 nM) 1 * 5 mg

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A fluorinated pyrimidine and derivative of fluorouracil that has anti-neoplastic activity and is commonly used as adjuvant therapy f ollowing resection for some forms of cancer 1 * 5 g

Supplier: CAYMAN

A fluorinated pyrimidine and derivative of fluorouracil that has anti-neoplastic activity and is commonly used as adjuvant therapy f ollowing resection for some forms of cancer 1 * 5 g