Organic reference standard, Spermine, analytical standard, Supelco®
55513-100MG
: Merck
:
- Pk:100 mg
- Standards:Analytical standard
- CAS No.:71-44-3
- Description:Spermine, ≥99,0% (GC), 97,0 - 103,0% (T)
- Melting point:28...30 (lit.)
- Formula:C₁₀H₂₆N₄
- Storage temperature:2...8 °C
- Description:Spermine
- Boiling point:150 °C/5 mmHg(lit.)
- Form:Neat
Mixed NMDA glutamate receptor agonist/antagonist at the polyamine site. Neuroprotective effects have been observed at high concentrations (1 mM), while neurotoxicity is observed at lower concentrations. It enhances agonist effectiveness at the strychnine-insensitive glycine site. Plays a role in cellular proliferation and differentiation, inhibits neuronal nitric oxide synthase (nNOS).