Pharmaceutical secondary standard, Metformin hydrochloride, (CRM), Supelco®

PHR1084-500MG

: Merck

Pharmaceutical secondary standard, Metformin hydrochloride, (CRM), Supelco®

PHR1084-500MG

: Merck

Pack type:
Glass bottle for solids
Pk:
500 mg
CAS No.:
1115-70-4
Melting point:
223-226 °C (lit.)
Formula:
NH₂C(=NH)NHC(=NH)N(CH₃)₂ · HCl
Description:
Metformin hydrochloride
Form:
Neat

Metformin is an antidiabetic agent that reduces blood glucose levels and improves insulin sensitivity.

Traceable to PhEur M0605000
Traceable to USP 1396309

Its metabolic effects, including the inhibition of hepatic gluconeogenesis, are mediated at least in part by activation of the LKB1-AMPK (AMP-activated protein kinase) pathway. Activation of this pathway also appears to be involved in the antiproliferative and proapoptotic actions of metformin in cancer cell lines.

: This product was designed, produced and verified for accuracy and stability in accordance with ISO/IEC 17025:2005 (AClass Cert AT-1467), ISO GUIDES 34:2009 (AClass Cert AR-1470).