You searched for: Proteins and Peptides
Proteins are used in routine laboratory procedures such as binding enzymes or coupling peptides to carrier proteins. These kits, mixture solutions, and collagen matrices fulfill a myriad of essential laboratory functions for developing relationships between proteins and other cellular components. The stimulating proteins offered have various amino acid arrangements and functions to fulfill any sample manipulation for testing purposes in any field.
DYRK kinase substrate
Supplier: ENZO LIFE SCIENCES
This peptide (also known as Woodtide), KKISGRLSPIMTEQ, is derived from transcription factor FKHR with the addition of two lysines to facilitate binding to phosphocellulose membranes. It is a substrate for the DYRK family of kinases.
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Human recombinant EGF (from P. pastoris)
Supplier: Apollo Scientific
Recombinant HuEGF produced in Pichia Pastoris, lypohilized powder >98% (HPLC, SDS-PAGE)
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Human recombinant p62 (GST-tag),GST Tag
Supplier: ENZO LIFE SCIENCES
Produced in E. coli. Human p62 (1-440 aa) is fused to a N-terminal GST-tag.
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Mouse recombinant netrin 1
Supplier: ENZO LIFE SCIENCES
Produced in HEK 293 cells. The extracellular domain of mouse netrin-1 (aa 27-604) is fused at the C-terminus to a FLAG®-tag.
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Microcystis aeruginosa Microcystin LF
Supplier: ENZO LIFE SCIENCES
Microcystins are a group of cyclic heptapeptide hepatotoxins produced by a number of cyanobacterial genera. The most notable of which, and namesake, is the widespread genus Microcystis. Structurally, all microcystins consist of the generalized structure cyclo(-D-Ala1-X2-D-MeAsp3-Y4-Adda5-D-Glu6-Mdha7-). X and Y are variable L-amino acids, D-MeAsp is D-erythro-ß-methylaspartic acid and Mdha is N-methyldehydroalanine. Adda is the cyanobacteria unique C20 ß-amino acid 3-amino-9-methoxy-2,6,8-trimethyl-10-phenyl-deca-4,6-dienoic acid. Substitutions of the variable L-amino acids at positions 2 and 4 give rise to at least 21 known primary microcystin analogs and alterations in the other constituent amino acids result in more than 90 reported mycrocystins to date.
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Human cathepsin G (from Neutrophils)
Supplier: ENZO LIFE SCIENCES
Isolated from human neutrophils. Active enzyme. Negative for HbsAg, anti-HBc, anti-HCV, and anti-HIV-1 and -2.
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Human Recombinant EDA-A1 (soluble) (from E. coli)
Supplier: ENZO LIFE SCIENCES
Produced in E. coli. The extracellular domain of human EDA-A1 (ectodysplasin-A1) (aa 245-391) is fused at the N-terminus to a linker peptide (9 aa) and a FLAG®-tag.
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Proteasome inhibitor II aldehyde
Supplier: ENZO LIFE SCIENCES
Potent and cell permeable proteasome inhibitor. Inhibits the chymotrypsin-like activity of the 26S proteasome (MCP; multicatalytic proteinase complex). Does not inhibit the peptidylglutamyl-peptide hydrolyzing activity of the MPC.
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Human Recombinant 14-3-3eta (from E. coli), HIS Tag
Supplier: ENZO LIFE SCIENCES
Produced in E. coli. Human 14-3-3η is fused at the C-terminus to a His-tag.
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Recombinant dengue NS1 ST3
Supplier: ENZO LIFE SCIENCES
Dengue virus NS1 protein serotype 3 presented in its native folded state with all post-translational modifications to deliver optimal antigenicity.
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Human recombinant CD30:Fc
Supplier: ENZO LIFE SCIENCES
Produced in HEK 293 cells. The cysteine-rich region of human CD30 (Ki-1) (aa 1-380) is fused to the Fc portion of human IgG1 .
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Human Recombinant SCF (CTGrade GMP) (from E. coli)
Supplier: SHENANDOAH BIOTECHNOLOGY
SCF is a multipotent factor which affects cells of the myeloid, erythroid, mast, and lymphoid lineages.
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Di-Ubiquitin (linear) (from E. coli)
Supplier: ENZO LIFE SCIENCES
Linear polyubiquitin chains are useful tools for investigating, amongst other things, the specificity and reactivity of deubiquitinylating enzymes (DUBs) and the recognition and interaction of linear polyubiquitin modified proteins with ubiquitin binding domain (UBDs) containing proteins.
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Mouse recombinant TNC:TWEAK (soluble)
Supplier: ENZO LIFE SCIENCES
Produced in HEK 293 cells. The extracellular domain of mouse TWEAK (aa 94-249) is fused at the N-terminus to tenascin-C (TNC) (chicken) (aa 110-139) and a FLAG®-tag.
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Human catestatin
Supplier: ENZO LIFE SCIENCES
Human Chromogranin A [352-372]). Wild type catestatin, initially described as a potent catecholamine release inhibitory peptide. Cst located in the skin is active against Gram-negative and Gram-positive bacteria as well as against fungi and yeast. Also proposed as a modulator or regulator of cardiac function and as an anti-hypertensive agent.
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Mouse recombinant LAG-3:Fc (from CHO cells)
Supplier: ENZO LIFE SCIENCES
Produced in CHO cells. The sequence coding for the 4 extracellular Ig-like domains of mouse LAG-3 (D1-D4) is fused to the Fc portion of mouse IgG2a (hinge-CH2-CH3).
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Human recombinant CD40L, soluble
Supplier: ENZO LIFE SCIENCES
Can be used to activate human B cells and dendritic cells. Stimulates growth of human B cells. For stimulation of mouse cells via CD40 use MAb to CD40 (mouse) (FGK45) (Prod. No. ALX-805-046).
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Caspase inhibitor set III
Supplier: ENZO LIFE SCIENCES
Synthetic peptides that irreversibly inhibit the activity of each of the caspase-family proteases. YVAD is the recognition sequence for caspase-1/ICE, VDVAD is the recognition sequence for caspase-2, DEVD is the recognition sequence for caspase-3/CPP32, WEHD is the recognition sequence for caspase-5, VEID is the recognition sequence for caspase-6/Mch2, IETD is the recognition sequence for caspase-8/FLICE, LEHD is the recognition sequence for caspase-9, and VAD is the recognition sequence for a caspase(s) that functions upstream of most other caspases.
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Human Recombinant FLT-3 (CTGrade GMP) (from E. coli)
Supplier: SHENANDOAH BIOTECHNOLOGY
IL-6 is an important pro-inflammatory and anti-inflammatory cytokine expressed by T cells, macrophages, and muscle cells. Signals through a receptor complex containing two receptors, IL-6Rα and gp130. Plays an important function in promoting fever and can serve to stimulate an immune response to trauma.
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Recombinant Rat Thioredoxin Reductase 1
Supplier: SELENOZYME
The rat TrxR1 selenoprotein is encoded by the rat Txnrd1 gene and exerts a wide range of functions in cytosolic redox control and antioxidant systems.
We provide the main cytosolic isoform of the rat TrxR1 enzyme with more than 90% Sec contents and more than 95% purity in aliquots at amounts from 5 to 50 units.
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Mouse Recombinant Mouse Glioma CultuPB (from E. coli)
Supplier: SHENANDOAH BIOTECHNOLOGY
Cytokines for cell culture of mouse glioma cells. A glioma is a generic term used to describe tumors that arise from the glia tissue of the brain that supports and surrounds neurons. Glioma tumor cells can be successfully cultured ex vivo with EGF, FGF-basic (or FGF-2), and PDGFs (AA and BB).
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Human recombinant MMP20 (catalytic domain) (from E. coli)
Supplier: ENZO LIFE SCIENCES
Produced in E. coli. Active recombinant matrix metalloproteinase-20 (MMP-20, enamelysin) cloned from human cDNA. The enzyme consists of residues Tyr108-Phe276 (NM_004771), which comprises the catalytic domain of human MMP-20, with a C-terminal purification tag. This represents a naturally-occurring active form of MMP-20 which lacks the C-terminal hemopexin domain.
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Human Recombinant TH9 Cell Polarizing PB (from E. coli)
Supplier: SHENANDOAH BIOTECHNOLOGY
Cytokines for mouse neuronal cell culture. Neural Stem Cells (NSC) are self-renewing cells, of the neural lineage, capable of generating neurons (GABA, dopamine and motor neurons), astrocytes and oligodenrocytes. NSCs are marked by expression of Nestin and can be derived from fetal neural stem cells, adult neural stem cells, embryonic stem cells and adult somatic cells.
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Horse Recombinant RE VEGF-165 (Animal free) (from E. coli)
Supplier: SHENANDOAH BIOTECHNOLOGY
FLT-3 Ligand is a growth factor that regulates proliferation of early hematopoietic cells. FLT-3 Ligand binds to cells expressing the tyrosine kinase receptor FLT-3. FLT-3 ligand by itself does not stimulate proliferation of early hematopoietic cells, but synergizes with other CSFs and interleukins to induce growth and differentiation. Unlike SCF, FLT-3 ligand exerts no activity on mast cells. Multiple isoforms of FLT-3 Ligand have been identified.
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Mouse Recombinant HSC Expansion PB (from E. coli)
Supplier: SHENANDOAH BIOTECHNOLOGY
Cytokines for polarizing T cells into T regulatory cells. T regulatory cells (Tregs) are a subset of T cells that suppress immune function. They are characterized by the expression of CD4, CD25 and Foxp3 and are known to produce immunosuppressive cytokines TGF-β 1 and IL-10. Tregs can be cultured from naive CD4+ T cells by culturing them in the presence of IL-2 and TGF-β 1 with CD3 and CD28 stimulation. In some cases cells are also cultured with neutralizing antibodies to IL-4, IFNγ and IL-12 and/or retinoic acid.
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ADAM Substrate
Supplier: ENZO LIFE SCIENCES
Fluorogenic substrate for ADAM8 (kcat/Km = 1,0×105 M-1s-1), ADAM10 (6,2×103), ADAM12 (2,8×105), TACE (TNF-α converting enzyme, ADAM17) (4,3×105), and likely other ADAMs, especially those that cleave TNF-α type sequences. Also efficiently cleaved by MMP-1, MMP-2, MMP-3, MMP-8, MMP-9, MMP-13, and MMP-14. FAM fluorescence is quenched by the Dabcyl group until cleavage separates them. Ex.: 485 nm, Em.: 530 nm. This substrate is useful for inhibitor screening and kinetic analysis.
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Human Recombinant NGAL (from Cells)
Supplier: PROSCI
LCN2 is iron-trafficking protein involved in multiple processes such as apoptosis, innate immunity and renal development. LCN2 binds iron through association with 2,5-dihydroxybenzoic acid (2,5-DHBA), a siderophore that shares structural similarities with bacterial enterobactin, and delivers or removes iron from the cell, depending on the context. LCN2 is involved in apoptosis due to interleukin-3 (IL3) deprivation: iron-loaded form increases intracellular iron concentration without promoting apoptosis, while iron-free form decreases intracellular iron levels, inducing expression of the proapoptotic protein BCL2L11/BIM, resulting in apoptosis. LCN2 is involved in innate immunity, possibly by sequestrating iron, leading to limit bacterial growth.