Bisindolylmaleimide I ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Potent and selective protein kinase C inhibitor which has been used effectively in platelets, Swiss 3T3 fibroblasts and macrophages. Inhibitory profile: PKC, IC50=0.02µM (inhibits α, ßI, ßII and γ subtypes with similar potency); PKA, IC50=2.0µM; phosphorylase kinase, IC50=0.7µM; insulin, EGF and PDGF receptor tyrosine kinases are not inhibited at concentrations up to 50µM.
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Bisindolylmaleimide I
Supplier: Thermo Fisher Scientific
Very potent and selective inhibitor of protein kinase C.