Anti-MARCH2 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalog # BOSSBS-9336R-A350

Supplier: BIOSS INC

Catalog # BOSSBS-9336R-A350

Supplier: BIOSS INC

Specifications

Antibody type:
Primary
Antigen name:
Membrane-associated ring Finger (C3HC4) 2, E3 ubiquitin protein ligase
Antigen symbol:
MARCH2
Clonality:
Polyclonal
Conjugation:
Alexa Fluor® 350
Host:
Rabbit
ImmunoChemistry:
Yes
Isotype:
IgG
Reactivity:
Human,
Rat,
Mouse
Cross adsorption:
No
Form:
liquid
Gene ID:
51257
Antigen synonyms:
RNF172|MARCH-II|HSPC240
Storage buffer:
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Storage temperature:
Store at –20 °C for 12 months
Concentration:
1 μg/μl
Shipping temperature:
4°C
Purification:
Purified by Protein A
Pk:
100 µl

Specifications

About this item

Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). MARCH2 (membrane-associated ring finger (C3HC4) 2), also known as RNF172 or HSPC240, is a 246 amino acid multi-pass membrane protein that localizes to the endoplasmic reticulum and contains one RING-CH-type zinc finger. Expressed in a variety of tissues, MARCH2 functions as an E3 ubiquitin-protein ligase that is thought to mediate the ubiquitination and subsequent degradation of CD71 and B7-2 and may be involved in endosomal protein trafficking.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: MARCH2
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 350
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat