Specifications
- Antibody type:Primary
- Antigen name:NMUR1/GPR66
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 680
- Flow cytometry:Yes
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Epitope:31-80/426
- Form:Liquid
- Gene ID:10316
- Antigen synonyms:Neuromedin-U receptor 1|NMU-R1|Growth hormone secretagogue receptor family Member 3|G-protein coupled receptor 66|GPR66|G-protein coupled receptor FM-3|FM-3|Neuromedin U Receptor 1|G protein-coupled receptor 66|NMUR1|NMUR1_HUMAN
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:47 kDa
- Storage temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human NMUR1
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
Specifications
About this item
Neuromedin U is a neuropeptide with high activity on smooth muscle. It is widely expressed in gastrointestinal systems and central nervous system (CNS). Peripheral activities of neuromedin U include smooth muscle stimulation, ion transport alterations in the gut and the regulation of local blood flow and adrenocortical function. Neuromedin U receptors 1 and 2 (NMUR1 and NMUR2) are multi-pass membrane proteins that belong to the G-protein coupled receptor 1 family of proteins. Both NMUR1 and NMUR2 act as receptors for the neuromedin U neuropeptide. NMUR1 is detected in peripheral organs, particularly in urogenital and gastrointestinal systems, with highest levels in testis. It's expression in CNS is low, but the protein has been detected in cerebellum, hippocampus, dorsal root ganglia and spinal cord. NMUR2 is predominantly detected in central nervous system with highest levels detected in medulla oblongata, spinal cord and thalamus. It may also be detected in testis but has low levels of expression in peripheral tissues.
Type: Primary
Antigen: NMUR1/GPR66
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 31-80/426
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
Supplier: VWR Chemicals
Supplier: HEATHROW
Supplier: VWR Chemicals
Supplier: VWR Chemicals
Supplier: VWR Collection
Supplier: VWR Collection
Supplier: KIMBERLY CLARK
Supplier: VWR Collection
Supplier: VWR Collection
Supplier: VWR Collection
Supplier: VWR Chemicals