496220 Results for: "Total Dietary Fiber Kit Reagent Kit for 100 Determinations"

Supplier: MP Biomedicals

L-Glutamine, the uncharged and amidated analog of L-glutamic acid, is an important amino acid for the incorporation of NH4+ into biomolecules. It is biosynthesized from NH4+ and glutamate via the enzyme glutamate synthetase. In turn, degradation of glutamine to free the ammonia moiety is mediated by glutaminase. Glutamine also participates in acid-base regulation in vivo.

Supplier: MP Biomedicals

Collagenases degrade native helical collagen fibrils. The enzyme has an important role in connective tissue metabolism and is produced by specific cells involved in repairs and remodelling processes. It is a type II enzyme that contains greater clostripain activity. It is generally used for heart, bone, muscle, thyroid, cartilage, and liver cells. Ca²⁺ is required for its activation while metal chelating agents such as cysteine, EDTA or o-phenanthroline inhibits its activity.

Supplier: THERMO ELECTRON LED

The VersaCool™ Refrigerated circulating bath features a new headless design, suitable for use as a recirculating refrigerated bath or heated circulator to circulate fluid from the bath to specific applications.

Supplier: ProSci Inc.

PLIN coats lipid storage droplets in adipocytes, thereby protecting them until they can be broken down by hormone-sensitive lipase. The protein is the major cAMP-dependent protein kinase substrate in adipocytes and, when unphosphorylated, may play a role in the inhibition of lipolysis.The protein encoded by this gene coats lipid storage droplets in adipocytes, thereby protecting them until they can be broken down by hormone-sensitive lipase. The encoded protein is the major cAMP-dependent protein kinase substrate in adipocytes and, when unphosphorylated, may play a role in the inhibition of lipolysis.

Supplier: ProSci Inc.

CD279 (Programmed Cell Death Protein 1; PD-1) is a type I transmembrane protein belonging to the CD28/CTLA-4 family of immunoreceptors that mediate signals for regulating immune responses. Members of the CD28/CTLA-4 family have been shown to either promote T cell activation (CD28 and ICOS) or downregulate T cell activation (CTLA-4 and PD-1). CD279 is expressed on activated T cells, B cells, myeloid cells and on a subset of thymocytes. In vitro, ligation of CD279 inhibits TCR-mediated T cell proliferation and production of IL-1, IL-4, IL-10 and IFN-gamma. In addition, CD279 ligation also inhibits BCR mediated signallling. CD279 deficient mice have a defect in peripheral tolerance and spontaneously develop autoimmune diseases.

Supplier: ProSci Inc.

IL18RAP is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding activity of IL18R1 (IL1RRP), a ligand binding subunit of IL18 receptor. The coexpression of IL18R1 and this protein is required for the activation of NF-kappaB and MAPK8 (JNK) in response to IL18.The protein encoded by this gene is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding activity of IL18R1 (IL1RRP), a ligand binding subunit of IL18 receptor. The coexpression of IL18R1 and this protein is required for the activation of NF-kappaB and MAPK8 (JNK) in response to IL18.

Supplier: ProSci Inc.

Proprotein convertase subtilisin/kexin type 9 (PCSK9) is also known as NARC1 (neural apoptosis regulated convertase), is a newly identified subtilase belonging to the peptidase S8 subfamily. Mouse PCSK9 is synthesized as a soluble zymogen, and undergoes autocatalytic intramolecular processing in the endoplasmic reticulum, resulting in the cleavage of its propeptide that remains associated with the secreted active enzyme with a broad alkaline pH optimum. This protein plays a major regulatory role in cholesterol homeostasis. PCSK9 binds to the epidermal growth factor-like repeat A (EGF-A) domain of the low-density lipoprotein receptor (LDLR), inducing LDLR degradation. PCSK9 may also have a role in the differentiation of cortical neurons. Mutations in this gene have been associated with a rare form of autosomal dominant familial hypercholesterolemia (HCHOLA3).

Supplier: ProSci Inc.

Programmed cell death 1 ligand 1 (PDL1) is also known as B7-H, B7H1, MGC142294, MGC142296, PD-L1, PDCD1L1 and PDCD1LG1,which is a member of the growing B7 family of immune molecules and is involved in the regulation of cellular and humoral immune responses.PDL1 is a cell surface immunoglobulin superfamily with two Ig-like domains within the extracellular region and a short cytoplasmic domain. This protein is broadly expressed in the majority of peripheral tissues as well as hematopoietic cells. Interaction between PDL1 and its receptors belonging to the CD28 family of molecules provide both stimulatory and inhibitory signals in regulating T cell activation and tolerance. PDL1 may inhibit ongoing T-cell responses by inducing apoptosis and arresting cell-cycle progression.

Supplier: ProSci Inc.

PBEF1 catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein is an adipokine that is localized to the bloodstream and has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It also activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.

Supplier: ProSci Inc.

Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release.Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release. The single FST gene encodes two isoforms, FST317 and FST344 containing 317 and 344 amino acids respectively, resulting from alternative splicing of the precursor mRNA. In a study in which 37 candidate genes were tested for linkage and association with polycystic ovary syndrome (PCOS) or hyperandrogenemia in 150 families, evidence was found for linkage between PCOS and follistatin.

Supplier: ProSci Inc.

The protein encoded by BAD gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.

Supplier: ProSci Inc.

Semaphorin-4A (SEMA4A) is also known as Semaphorin-B (SEMAB), which belongs to the semaphorin family. SEMA4A contains one Ig-like C2-type (immunoglobulin-like) domain, one PSI domain and one sema domain. SEMA4A is cell surface receptor for PLXNB1, PLXNB2, PLXNB3 and PLXND1 that plays an important role in cell-cell signaling. SEMA4A plays a role in priming antigen-specific T-cells, promotes differentiation of Th1 T-helper cells, and thereby contributes to adaptive immunity. SEMA4A also promotes phosphorylation of TIMD2 and inhibits angiogenesis. SEMA4A promotes axon growth cone collapse and inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons.

Supplier: Spectrum Chemical

Thiamine Hydrochloride, FCC is the hydrochloride salt of vitamin B1 and used to treat or prevent vitamin B1 deficiency. The FCC grade meets the requirements of the Food Chemical Codex indicates and is suitable for all food, beverage and nutritional supplement applications. Spectrum Chemical offers over 300 Food grade chemical ingredients packaged in laboratory size bottles to production drum quantities and are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities.

Supplier: GESTIGKEIT HARRY

Cast iron GG15 plate. Robust hot plate designed for continuous operation with automatic control for precise temperatures from 20 to 450 °C, has four adjustable feet for extra stability. The required temperature is set via the digital controller and automatically remains constant. The actual temperature is displayed continuously via easy to read display.

Supplier: Merck

PIPES monosodium salt, Sigma-Aldrich®

Supplier: QUARTZTECHNISCHE WERKSTATTEN

TUBE DIGESTION 100ML QUARTZGLASS 1 * 1 items

Supplier: Roth Carl

Set of weights OIML-Class M2 1 * 1 items

Supplier: HAMMERBACHER

Regal mit Türen 7100 RE, 5 OH, Korpus: grau / Front: grau, 80 x 42 x 200, 4 cm (BxTxH), Drehtüre 5 OH, Öffnungswinkel 110°, nicht ab schließbar, Relinggriff RE, höhenjustierbar durch den Boden 0-10mm, Sockelblende 10 cm hoch, Anlieferzustand: zerlegt 1 * 1 ST

Supplier: KIND ARBEITSSICHERHEIT

JACKE DECONTEX CONCEPT 2810 ROT 2XL mit Umlegekragen ca. 90 cm Norm: EN 14605 Typ 4, EN 1149, EN 14116 Lieferbare Größen: L - XXL (M und XXXL auf Anfrage) Übergrößenzuschlag: Gr. XL + 5%, Gr. XXL + 10%, Gr. XXXL + 15% 1 * 1 ST

Supplier: KIRSCH PHILIPP

SENSOR TEMPERATURE PT100 1 * 1 items

Supplier: HAMILTON BONADUZ

HV plug valves provide an economical and flexible method of custom-building a fluid flow control system, from a simple on/off valve to a more complex multi-valve arrangement, using a combination of loop and distribution valves.

Supplier: FRISTADS KANSAS

Fristads Kansas ICON bib trousers workwear for crafts and trades.

Supplier: Testo

The testo 476 hand-held xenon stroboscope with high-intensity light allows fast-moving objects to appear in slow motion. In doing so, the hand-held stroboscope measures and checks rotational and vibratory movements.

Supplier: Corning

The fluorescent dye DiIC12(3) can be used to label cells when performing analyses such as tumour cell invasion, endothelial cell migration, endothelial cell tubulogenesis, and other cell-based assays. DiIC12(3) is a lipophilic neuronal tracer that is commonly used for labelling neuronal projections as well as lipid bilayers in other cell types. Because DiIC12(3) exhibits low toxicity and minimal effects on cell viability, this dye can be used to pre-label cells for a variety of applications.

Supplier: MP Biomedicals

SDS is an detergent typically used to solubilize and denature proteins for electrophoresis. SDS has also been used in large-scale phenol extraction of RNA to promote the dissociation of protein from nucleic acids when extracting from biological material. SDS is used in Protein Electrophoresis & Blotting.

Supplier: MP Biomedicals

Sulfamethazine is an antibiotic used to clinically treat bronchitis, prostatitis and urinary tract infections. It is used in disposition and depletion kinetic studies. It is used to develop detection techniques for quantification in fluids such as cows’ milk, honey and swine urine.
Sulfamethazine is an antimicrobial sulfur drug that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase. Sulfamethazine is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA), which is required for bacterial synthesis of folic acid. It induces CYP3A4 expression and is acetylated by N-acetyltransferase. It exhibits sex dependent pharmacokinetics, metabolized by the male specific isoform CYP2C11. Sulfamethazine is bacteriostatic.

Supplier: ProSci Inc.

Programmed Death-1 (PD-1, CD279) is a type I transmembrane protein belonging to the CD28/CTLA-4 family of immunoreceptors that mediate signals for regulating immune responses. Members of the CD28/CTLA-4 family have been shown to either promote T cell activation (CD28 and ICOS) or downregulate T cell activation (CTLA-4 and PD-1). CD279 is expressed on activated T-cells, B-cells, myeloid cells and on a subset of thymocytes. In vitro, ligation of CD279 inhibits TCR-mediated T-cell proliferation and production of IL-1, IL-4, IL-10 and IFN-gamma. In addition, CD279 ligation also inhibits BCR mediated signallling. CD279 deficient mice have a defect in peripheral tolerance and spontaneously develop autoimmune diseases.

Supplier: ProSci Inc.

T cells require a signal induced by the engagement of the T cell receptor and a costimulatory signal(s) through distinct T cell surface molecules for optimal T cell activation and tolerance. CD273 (PD-L2) is one of two ligands for programmed death-1 (PD-1; CD279), a member of the CD28 family of immunoreceptors. The other identified ligand is PD-L1. CD273 is broadly expressed and also up regulated in a variety of tumour cell lines. On previously activated T cells, CD273 interaction with PD-1 inhibits TCR mediated proliferation and cytokine production, suggesting an inhibitory role in regulating immune responses. CD273 has a costimulatory function on resting T cells activated with suboptimal TCR signals.

Supplier: ProSci Inc.

T cells require a signal induced by the engagement of the T cell receptor and a costimulatory signal(s) through distinct T cell surface molecules for optimal T cell activation and tolerance. CD273 (PD-L2) is one of two ligands for programmed death-1 (PD-1; CD279), a member of the CD28 family of immunoreceptors. The other identified ligand is PD-L1. CD273 is broadly expressed and also up regulated in a variety of tumour cell lines. On previously activated T cells, CD273 interaction with PD-1 inhibits TCR mediated proliferation and cytokine production, suggesting an inhibitory role in regulating immune responses. CD273 has a costimulatory function on resting T cells activated with suboptimal TCR signals.

Supplier: FRISTADS KANSAS

Overalls made from 65% polyester and 35% cotton, with soft nap on reverse side.