495862 Results for: "Total Dietary Fiber Kit Reagent Kit for 100 Determinations"
Anti-SCN2B Rabbit Polyclonal Antibody (Alexa Fluor® 555)
Supplier: Bioss
Voltage-gated sodium channels are selective ion channels that regulate the permeability of sodium ions in excitable cells. During the propagation of an action potential, sodium channels allow an influx of sodium ions, which rapidly depolarizes the cell. Na+ CP type II beta(sodium channel, voltage-gated, type II, beta), also known as SCN2B, is a 215 amino acid single-pass type I membrane protein that plays a critical role in the expression and assembly of the heterotrimeric complex of the sodium channel and interacts with Tenascin-R to influence the clustering and regulation of sodium channels at nodes of Ranvier. Expressed specifically in brain, Na+ CP type II beta contains one Ig-like C2-type (immunoglobulin-like) domain and is encoded by a gene that maps to human chromosome 11q23.3 and mouse chromosome 9 A5.2.
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Anti-GRIK2 Rabbit Polyclonal Antibody (Cy3®)
Supplier: Bioss
Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate, whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions. The NMDA receptors consist of five subunits: epsilion 1, 2, 3, 4 and one zeta subunit. The zeta subunit is expressed throughout the brainstem, whereas the four epsilon subunits display limited distribution.
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Anti-GRIK3 Rabbit Polyclonal Antibody (Alexa Fluor® 350)
Supplier: Bioss
Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate, whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions. The NMDA receptors consist of five subunits: epsilion 1, 2, 3, 4 and one zeta subunit. The zeta subunit is expressed throughout the brainstem, whereas the four epsilon subunits display limited distribution.
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Anti-NTR2 Rabbit Polyclonal Antibody (Alexa Fluor® 488)
Supplier: Bioss
Neurotensin (NT) initiates an intracellular response by interacting with the G protein-coupled receptors NTR1 (NTS1 receptor, high affinity NTR) and NTR2 (NTS2 receptor, levocabastine-sensitive neurotensin receptor), and the type I receptor NTR3 (NTS3 receptor, sortilin-1, Gp95). NT has a wide distribution in regions of the brain and in peripheral tissues where NT receptors can contribute to hypotension, hyperglycemia, hypothermia, antinociception and regulation of intestinal motility and secretion. HL-60 cells express NTR1, which can couple to Gq, Gi/o, or Gs. Alternative splicing of rat NTR2 can generate a 5-transmembrane domain variant isoform that is co-expressed with the full-length NTR2 throughout the brain and spinal cord. NTR3 activation in the murine microglial cell line N11 induces MIP-2, MCP-1, IL-1beta and TNF?in an ERK1/2 and Akt kinase-dependent manner.
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Anti-GRIK2 Rabbit Polyclonal Antibody (Alexa Fluor® 488)
Supplier: Bioss
Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate, whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions. The NMDA receptors consist of five subunits: epsilion 1, 2, 3, 4 and one zeta subunit. The zeta subunit is expressed throughout the brainstem, whereas the four epsilon subunits display limited distribution.
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Temperature and Pressure Data Loggers for Process Validation, EBI 12-TP322 or -TP422
Supplier: EBRO
Both data loggers are high-precision temperature and pressure loggers designed for process validation in steam sterilisers, batch control, and pharmaceutical applications. With a wide temperature and pressure range and high accuracy, they provide reliable data logging for critical monitoring processes in sterilisation, healthcare, production, and pharmaceutical environments, ensuring accurate validation and quality control.
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Anti-RNF122 Rabbit Polyclonal Antibody
Supplier: Bioss
Sortilin-related receptor, also known as Sorting protein-related receptor containing LDLR class A (SorLA), is a Type I membrane protein that may be involved in cell-cell interaction. SorLA, a single transmembrane receptor, binds LDL (the main cholesterol-carrying lipoprotein of plasma) and transports it into cells by endocytosis. SorLA is synthesized as a proreceptor which is processed to the mature form by a furin-like propeptidase. It can also bind to RAP, receptor-associated protein. SorLa is a multifunctional endocytis receptor important in lipoprotein and protease uptake. The N-terminal propeptide, which is removed, can be cleaved by furin or homologous proteases. Endogenous sorLA binds the neuropeptide head activator (HA) and is important for HA signaling and function. It is expressed mainly in brain (cerebral cortex, cerebellum and the occipital pole), but can also be found in liver, spinal cord, kidney, testis and pancreas.
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Rauwolscine is a natural alkaloid that acts as a selective and reversible 2-adregenergic receptor antagonist (Ki = 12 nM).{25653} I t is a stereoisomer of yohimbine, which potently antagonizes both 1- and 2-adrenergic receptors.{25653} Rauwolscine 1 * 250 mg
Supplier: Cayman Chemical
Rauwolscine is a natural alkaloid that acts as a selective and reversible 2-adregenergic receptor antagonist (Ki = 12 nM).{25653} I t is a stereoisomer of yohimbine, which potently antagonizes both 1- and 2-adrenergic receptors.{25653} Rauwolscine 1 * 250 mg
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Magnetic bar, length 100cm, width 4cm 1 * 1 items
Supplier: KOEHLER TECHNISCHE PRODUKTEN
Magnetic bar, length 100cm, width 4cm 1 * 1 items
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Tip ejector upr part 10ml focus darkblue 1 * 1 items
Supplier: Thermo Fisher Scientific
Tip ejector upr part 10ml focus darkblue 1 * 1 items
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BOND ELUT-ENV, 100MG 1ML, TABLESS,10 1 * 1 items
Supplier: VARIAN
BOND ELUT-ENV, 100MG 1ML, TABLESS,10 1 * 1 items
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Test Sieve 100X40mm 150µm ISO 3310/1 stainless steel 1 * 1 items
Supplier: Retsch GmbH
Test Sieve 100X40mm 150µm ISO 3310/1 stainless steel 1 * 1 items
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PU-Sicherheitsstiefel EN ISO 20345 S4 CI Spezialstiefel mit dicker Schaftwand und dicker Sohle aus geschäumten Polyurethan, Stahlkappe Kälteisolation bis minus 40 Grad Schaft: grün, Sohle: schwarz Gewicht: 3 kg/Paar Schafthöhe: zirka 39 cm Größen: 39 1 * 1 PAAR
Supplier: FELDTMANN HELMUT
PU-Sicherheitsstiefel EN ISO 20345 S4 CI Spezialstiefel mit dicker Schaftwand und dicker Sohle aus geschäumten Polyurethan, Stahlkappe Kälteisolation bis minus 40 Grad Schaft: grün, Sohle: schwarz Gewicht: 3 kg/Paar Schafthöhe: zirka 39 cm Größen: 39 1 * 1 PAAR
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THERMOSHAKER 1500-PRO 1 * 1 items
Supplier: witeg Labortechnik
THERMOSHAKER 1500-PRO 1 * 1 items
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BOX STORAGE PP NEONROT/PINK 1 * 1 items
Supplier: USA SCIENTIFIC PLASTICS
BOX STORAGE PP NEONROT/PINK 1 * 1 items
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Tubing threaded 100x130x3.5mm gl90 ,with restriction,acc. to din 12216, with iso screw thread,made of borosilicate glass 1 * 1 items
Supplier: witeg Labortechnik
Tubing threaded 100x130x3.5mm gl90 ,with restriction,acc. to din 12216, with iso screw thread,made of borosilicate glass 1 * 1 items
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ALSINTTUBE 99.7 OPEN 25X18X100 MM 1 * 1 items
Supplier: MORGAN ADVANCED MATERIALS HALD
ALSINTTUBE 99.7 OPEN 25X18X100 MM 1 * 1 items
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NOVAPOLY COVER 1 * 12 items
Supplier: MICRONOVA
NOVAPOLY COVER 1 * 12 items
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Tubing, butyl 12x 16mm black rubber. 1 * 1 m
Supplier: DEUTSCH NEUMANN
Tubing, butyl 12x 16mm black rubber. 1 * 1 m
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CO-2 BURETTE(FINE MEASURING BRUSH) 100ML 1 * 1 items
Supplier: NEUBERT VOLUME GLASSWAERE
CO-2 BURETTE(FINE MEASURING BRUSH) 100ML 1 * 1 items
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FP DIGITAL TIP EJECTOR LOWER PART 10 1 * 1 items
Supplier: Thermo Fisher Scientific
FP DIGITAL TIP EJECTOR LOWER PART 10 1 * 1 items
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CHIRALCEL® OD-3R 50 x 2,1 mm 3 µm Analytical Column 1 * 1 items
Supplier: CHIRAL TECHNOLOGIES
CHIRALCEL® OD-3R 50 x 2,1 mm 3 µm Analytical Column 1 * 1 items
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GLOVE CRYO WATERPR.MID-ARM 40CM PINK M/9 1 * 1 PAIR
Supplier: TEMPSHIELD
GLOVE CRYO WATERPR.MID-ARM 40CM PINK M/9 1 * 1 PAIR
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FLASK SULFONATION, 100ML, ST29/32, WITH 4SIDE NECKS ST19/26 1 * 1 items
Supplier: witeg Labortechnik
FLASK SULFONATION, 100ML, ST29/32, WITH 4SIDE NECKS ST19/26 1 * 1 items
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RACKS TUBE 2ML FOR ESP151, SET 1 * 1 items
Supplier: Air Liquide
RACKS TUBE 2ML FOR ESP151, SET 1 * 1 items
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PK100 PRECLEANED 22ML CLEAR SCREW CAP VI AL 1 * 1 Each
Supplier: Merck
PK100 PRECLEANED 22ML CLEAR SCREW CAP VI AL 1 * 1 Each
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Anti-MELK Rabbit Polyclonal Antibody
Supplier: Bioss
Serine/threonine-protein kinase involved in various processes such as cell cycle regulation, self-renewal of stem cells, apoptosis and splicing regulation. Has a broad substrate specificity; phosphorylates BCL2L14, CDC25B, MAP3K5/ASK1 and ZNF622. Acts as an activator of apoptosis by phosphorylating and activating MAP3K5/ASK1. Acts as a regulator of cell cycle, notably by mediating phosphorylation of CDC25B, promoting localization of CDC25B to the centrosome and the spindle poles during mitosis. Plays a key role in cell proliferation and carcinogenesis. Required for proliferation of embryonic and postnatal multipotent neural progenitors. Phosphorylates and inhibits BCL2L14, possibly leading to affect mammary carcinogenesis by mediating inhibition of the pro-apoptotic function of BCL2L14. Also involved in the inhibition of spliceosome assembly during mitosis by phosphorylating ZNF622, thereby contributing to its redirection to the nucleus. May also play a role in primitive hematopoiesis.
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Anti-GALP/Alarin Rabbit Polyclonal Antibody
Supplier: Bioss
The galanin family of proteins are key members for inflammatory processes and cell proliferation, and may function as potential biomarkers for colon cancer. Produced in both neuronal and nonneuronal cells in the skin, members of the galanin family include galanin, galanin-message associated peptide, galanin-like peptide and alarin. GALP, also known as galanin-like peptide, is a 116 amino acid secreted protein belonging to the galanin family. Mainly produced in the arcuate nucleus of the hypothalamus (ARC) and the posterior pituitary, GALP is thought to function in CNS homeostatic processes, including the regulation of gonadotropin-releasing hormone secretion. GALP binds to the G-protein coupled galanin receptors, including GALR1, GALR2 and GALR3, and may also play a role in energy metabolism, with significant implications towards obesity. GALP exits as two alternatively spliced isoforms.
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Anti-RNF17 Rabbit Polyclonal Antibody
Supplier: Bioss
The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. RNF17 (ring finger protein 17) or tudor domain-containing protein 4, TDRD4, SPATA23, Mmip-2 or FLJ11045, is a testis-specific protein and and novel key regulator of spermiogenesis containing 1,623 amino acids. By distributing Mad proteins to the cytoplasm, RNF17 regulates the transcriptional activity of c-Myc. Although showing localization in the nucleus, RNF17 is predominantly observed in cytoplasm and is a component of a novel nuage found in male germ cells. The gene encoding RNF17 maps to human chromosome 13q12.12 and encodes one RING-type zinc finger and four tudor domains. As a result of alternative splice events, five RNF17 isoforms exisit.
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Anti-Salmonella typhimurium Rabbit Polyclonal Antibody
Supplier: Bioss
The genus Salmonella is a member of the family Enterobacteriaceae. The genus is composed of Gram-negative bacilli that are facultative and flagellated (motile). Salmonellae possess 3 major antigens; the "H" or flagellar antigen (phase 1 & 2), the "O" or somatic antigen (part of the LPS moiety) and the "Vi" or capsular antigen (referred to as "K" in other Enterobacteriaceae). Salmonellae also possess the LPS endotoxin characteristic of Gram-negative bacteria. This LPS is composed of an "O" polysaccharide ("O" antigen) an "R" core and the endotoxic inner "Lipid A". Endotoxins evoke fever and can activate complement, kinin and clotting factors. Until recently the most common cause of food poisoning by Salmonella species was due to S. Typhimurium. As its name suggests, it causes a typhoid-like disease in mice. In humans S. Typhimurium does not cause as severe disease as S. Typhi, and is not normally fatal. The disease is characterized by diarrhea, abdominal cramps, vomiting and nausea, and generally lasts up to 7 days.