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18933 results for "Pharma Synthesis, MilliporeSigma"

18933 Results for: "Pharma Synthesis, MilliporeSigma"

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Chloroform, dehydrated (max. 0.01% H₂O) 99.0-99.6% stabilised, GPR RECTAPUR® for synthesis

Chloroform, dehydrated (max. 0.01% H₂O) 99.0-99.6% stabilised, GPR RECTAPUR® for synthesis

Supplier: VWR Chemicals

Chloroform, dehydrated (max. 0.01% H₂O) 99.0-99.6% stabilised, GPR RECTAPUR® for synthesis

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TriLink® 2'-Deoxycytidine-5'-Triphosphate

TriLink® 2'-Deoxycytidine-5'-Triphosphate

Supplier: TriLink BioTechnologies

This nucleotide consists of an unmodified base, a deoxyribose, and a 5′ triphosphate group for synthesis of DNA molecules.

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TriLink® 2'-Deoxyguanosine-5'-Triphosphate

TriLink® 2'-Deoxyguanosine-5'-Triphosphate

Supplier: TriLink BioTechnologies

This nucleotide consists of an unmodified base, a deoxyribose, and a 5′ triphosphate group for synthesis of DNA molecules.

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4-(Hydroxymethyl)benzyl alcohol 98%

Supplier: Apollo Scientific

Intermediate for organic synthesis; Synthesis of high performance resin.

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3-Ethynylimidazo[1,2-b]pyridazine

Supplier: Apollo Scientific

Intermediate in Ponatinib synthesis.

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Dichloromethane, low water content ≥99.5% stabilised, BakerDRY™, J.T.Baker®

Dichloromethane, low water content ≥99.5% stabilised, BakerDRY™, J.T.Baker®

Supplier: Avantor

Specifically manufactured for use in organic, organometallic, and oligonucleotide synthesis requiring low water solvents.

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cDNA synthesis kits, AffinityScript

Supplier: AGILENT

Provides the highest efficiency of conversion of RNA to cDNA, fully optimised for qPCR applications.

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α-Chloro-o-xylene 98+%

Supplier: Apollo Scientific

Intermediate for organic synthesis.

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Anti-Protein Synthesis Initiation Factor 4E Binding Protein, Rabbit Polyclonal Antibody

Supplier: US Biological

Anti-Protein Synthesis Initiation Factor 4E Binding Protein, Rabbit Polyclonal Antibody

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Anti-Protein Synthesis Initiation Factor 4E Binding Protein, Rabbit Polyclonal Antibody

Supplier: US Biological

Anti-Protein Synthesis Initiation Factor 4E Binding Protein, Rabbit Polyclonal Antibody

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T7 RNA polymerase

Supplier: Thermo Fisher Scientific

T7 RNA polymerase is ideal for synthesis of unlabeled and labeled RNA. It catalyses the 5'→3' synthesis of RNA on either single-stranded DNA or double-stranded DNA downstream from it promoter. It is also used in the study of RNA secondary structure and RNA-protein interactions, RNA splicing.

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Methanol, low water content ≥99.8% (by GC, corrected for water content), BakerDRY™, J.T.Baker®

Methanol, low water content ≥99.8% (by GC, corrected for water content), BakerDRY™, J.T.Baker®

Supplier: Avantor

Specifically manufactured for use in organic, organometallic, and oligonucleotide synthesis requiring low water solvents.

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α-Chloro-p-xylene 99%

Supplier: Apollo Scientific

Intermediate for organic synthesis.

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di-Potassium hydrogen, anhydrous ≥98% for synthesis

di-Potassium hydrogen, anhydrous ≥98% for synthesis

Supplier: VWR Chemicals

, anhydrous ≥98% for synthesis

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N,N-Dimethylformamide ≥99.8% (by GC, corrected for water content), BakerDRY™ for organic synthesis, J.T.Baker®

N,N-Dimethylformamide ≥99.8% (by GC, corrected for water content), BakerDRY™ for organic synthesis, J.T.Baker®

Supplier: Avantor

N,N-Dimethylformamide ≥99.8% (by GC, corrected for water content), BakerDRY™ for organic synthesis, J.T.Baker®

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N-Benzoyl-2'-deoxyadenosine 98+%

Supplier: Thermo Fisher Scientific

Reactant in the synthesis of 2', 5'-Dideoxycytidines and Other Derivatives of 2'-Deoxycytidine. Reactant in the synthesis of Mono- and Diamino Analogues of 2?-Deoxyadenosine, Cordycepin, 9-(3-Deoxy-α-D-Threo-Pentofuranosyl)-Adenine and 9-(2-Deoxy-α-D-Threo-Pentofuranosyl)Adenine.

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1-Fluoro-2-nitrobenzene 98%

Supplier: Apollo Scientific

The activated fluorine reacts with arylamines to form 2-nitrodiarylamines see: Synthesis, 215 (1980)

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Inulin (from chicory root)

Inulin (from chicory root)

Supplier: Thermo Fisher Scientific

Inulin (from chicory root)

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4-Fluorobenzaldehyde 99%

Supplier: Apollo Scientific

Synthesis, 63 (1991): simple preparation of several 4-aryloxy phenols (via substitution then Baeyer-Villiger).

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Human recombinant tyrosinase (from E. coli)

Human recombinant tyrosinase (from E. coli)

Supplier: ENZO LIFE SCIENCES

Produced in E. coli. Tyrosinase is a copper-containing enzyme that catalyzes four steps in the melanin and catecholamine synthesis pathways.

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Anti-CERS2 Rabbit Polyclonal Antibody (Cy7®)

Supplier: Bioss

LASS2 (LAG1 homolog, ceramide synthase 2) has sequence similarity to yeast longevity assurance gene 1. It is thought to be involved in sphingolipid synthesis. Expression of LASS2 is transiently increased during the period of active myelination and is specifically localized to white matter tracts of the brain, including the Schwann cells of sciatic nerves suggesting that LASS2 is important for the synthesis of dihydroceramide used for synthesis of myelin sphingolipids. Expression of LASS2 in hepatocellular carcinoma cell lines suppresses the growth of cancer cells.

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Anti-CERS2 Rabbit Polyclonal Antibody (Cy3®)

Supplier: Bioss

LASS2 (LAG1 homolog, ceramide synthase 2) has sequence similarity to yeast longevity assurance gene 1. It is thought to be involved in sphingolipid synthesis. Expression of LASS2 is transiently increased during the period of active myelination and is specifically localized to white matter tracts of the brain, including the Schwann cells of sciatic nerves suggesting that LASS2 is important for the synthesis of dihydroceramide used for synthesis of myelin sphingolipids. Expression of LASS2 in hepatocellular carcinoma cell lines suppresses the growth of cancer cells.

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Terephthalaldehyde 98%

Supplier: Apollo Scientific

Synthesis of photopolymer.

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TriLink® 2'-Deoxythymidine-5'-Triphosphate

TriLink® 2'-Deoxythymidine-5'-Triphosphate

Supplier: TriLink BioTechnologies

This nucleotide consists of an unmodified base, a deoxyribose, and a 5′ triphosphate group for synthesis of DNA molecules.

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cDNA synthesis kits, qScript™

cDNA synthesis kits, qScript™

Supplier: Quantabio

qScript™ cDNA synthesis kit contains qScript™ Reverse Transcriptase, a mixture of a MMLV reverse transcriptase derivative and ribonuclease inhibitor protein, optimised for sensitive and reliable cDNA synthesis over a broad dynamic range of input RNA. cDNA synthesis reagents are provided in a variety of SuperMix and kit formats to suit specific applications.

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Azure B (azure I) ≥85% (by HPLC), prepared by direct synthesis, Sigma-Aldrich®

Supplier: SIGMA ALDRICH MICROSCOPY

Azure B has been used in M′Fadyean stain to visualize Bacillus anthracis capsule. Azure B is a cationic dye. It is part of the Romanowsky stain, which is used for staining of blood films. It is also used for the localisation of nucleic acids and lignin.

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Anti-MTOR Rabbit Polyclonal Antibody (Cy5®)

Supplier: Bioss

Serine/threonine protein kinase which is a central regulator of cellular metabolism, growth and survival in response to hormones, growth factors, nutrients, energy and stress signals. MTOR directly or indirectly regulates the phosphorylation of at least 800 proteins. Functions as part of 2 structurally and functionally distinct signaling complexes mTORC1 and mTORC2 (mTOR complex 1 and 2). Activated mTORC1 up-regulates protein synthesis by phosphorylating key regulators of mRNA translation and ribosome synthesis. This includes phosphorylation of EIF4EBP1 and release of its inhibition toward the elongation initiation factor 4E (eiF4E). Moreover, phosphorylates and activates RPS6KB1 and RPS6KB2 that promote protein synthesis by modulating the activity of their downstream targets including ribosomal protein S6, eukaryotic translation initiation factor EIF4B, and the inhibitor of translation initiation PDCD4. Stimulates the pyrimidine biosynthesis pathway, both by acute regulation through RPS6KB1-mediated phosphorylation of the biosynthetic enzyme CAD, and delayed regulation, through transcriptional enhancement of the pentose phosphate pathway which produces 5-phosphoribosyl-1-pyrophosphate (PRPP), an allosteric activator of CAD at a later step in synthesis, this function is dependent on the mTORC1 complex. Regulates ribosome synthesis by activating RNA polymerase III-dependent transcription through phosphorylation and inhibition of MAF1 an RNA polymerase III-repressor. In parallel to protein synthesis, also regulates lipid synthesis through SREBF1/SREBP1 and LPIN1. To maintain energy homeostasis mTORC1 may also regulate mitochondrial biogenesis through regulation of PPARGC1A. mTORC1 also negatively regulates autophagy through phosphorylation of ULK1. Under nutrient sufficiency, phosphorylates ULK1 at 'Ser-758', disrupting the interaction with AMPK and preventing activation of ULK1.

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Solvent-Resistant Stirred Cell for 47 mm Membranes

Solvent-Resistant Stirred Cell for 47 mm Membranes

Supplier: Merck

MilliporeSigma™ solvent-resistant stirred cells, for 47 mm membranes is used for protein desalting, purification and concentration.

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Acetonitrile, ultra-low water content ≥99.5% (by GC, corrected for water content), BakerDRY™, J.T.Baker®

Acetonitrile, ultra-low water content ≥99.5% (by GC, corrected for water content), BakerDRY™, J.T.Baker®

Supplier: Avantor

Specifically manufactured for use in organic, organometallic, and oligonucleotide synthesis requiring low water solvents.

   Sustainable Options Available
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Anti-CERS2 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Supplier: Bioss

LASS2 (LAG1 homolog, ceramide synthase 2) has sequence similarity to yeast longevity assurance gene 1. It is thought to be involved in sphingolipid synthesis. Expression of LASS2 is transiently increased during the period of active myelination and is specifically localized to white matter tracts of the brain, including the Schwann cells of sciatic nerves suggesting that LASS2 is important for the synthesis of dihydroceramide used for synthesis of myelin sphingolipids. Expression of LASS2 in hepatocellular carcinoma cell lines suppresses the growth of cancer cells.

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