"Other Essentials"

Supplier: Bioss

May contribute to neddylation of cullin components of SCF-type E3 ubiquitin ligase complexes. Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.

Supplier: Bioss

Flagellin is the subunit protein which polymerises to form the filaments of bacterial flagella. FlaB/D is not essential for polar flagellar synthesis and swimming motility. Homopolymer of FlaB/D is not able to form a functional filament.

Supplier: Abcam

Selective TRPC4 channel blocker (IC₅₀ = 0,96 (fluorescence assay) - 2,6 μM (electrophysiological assay)). Selective versus TRPC6 (19-fold) and TRPC5 (9-fold). Essentially inactive at TRPV1, TRPV3, TRPA1 and TRPM8 channels at concentrations up to 22 μM.

Supplier: Abcam

Essential amino acid which is necessary for normal growth in infants and for nitrogen balance in adults. Used as an antidepressant, anxiolytic and sleep aid. Precursor to niacin, indole alkaloids, serotonin and melatonin.

Supplier: Biotium

The amine reactive succinimidyl ester of EB (ethidium bromide) can be conjugated to peptides, proteins, drugs, polymeric materials and biomolecules with primary amine groups. The conjugates are expected to be essentially nonfluorescent until they are able to complex with nucleic acids, resulting in red fluorescence.

Supplier: Agrisera

Anti-Cyt c Rabbit Polyclonal Antibody

Supplier: Bioss

D-Aspartic acid is the D-isomer of aspartic acid also known as aspartate which is one of the 20 natural proteinogenic amino acids, the building blocks of proteins. As its name indicates, aspartic acid is the carboxylic acid analog of asparagine. It is non-essential in mammals, and might serve as an excitatory neurotransmitter in the brain. It is also a metabolite in the urea cycle, and participates in gluconeogenesis.

Supplier: Abcam

Highly sensitive, photo-stable fluorescent probe for quantification of low concentrations of nitric oxide (NO). More sensitive to nitric oxide (NO) than DAF-2, More photo-stable and less pH sensitive than DAF-2, Not as cell-permeable as the diacetate derivative, DAF-FM DA , but it does not need to be activated by cytosolic enzymes. Essentially nonfluorescent until it reacts with NO to form a fluorescent benzotriazole.

Supplier: Biotium

The amine reactive succinimidyl ester of TO (thiazole orange) can be conjugated to peptides, proteins, drugs, polymeric materials and biomolecules with primary amine groups. The conjugates are expected to be essentially nonfluorescent until they are able to complex with nucleic acids, resulting in green fluorescence.

Supplier: MP Biomedicals

YPD Broth is used for routine growth of Saccharomyces cerevisiae for molecular biology studies.

Supplier: MP Biomedicals

YPD broth or agar are used for routine growth of Saccharomyces cerevisiae for molecular biology studies.

Supplier: Bioss

In the process of endocytosis, essential rate-limiting regulator of a fast recycling pathway back to the plasma membrane. During cytokinesis, required for the postfurrowing terminal steps, namely for intercellular bridge stability and abscission, possibly by controlling phosphatidylinositol 4,5-bis phosphate (PIP2) and SEPT2 localisation at the intercellular bridge.

Supplier: Abcam

Widely used blue fluorescent thiol-reactive dye. Essentially non-fluorescent until it reacts with thiols, making it possible to quantify thiols without a separation step. Good energy acceptor from tryptophan and a good energy donor to fluorescein. Used to monitor release of thiols and to distinguish proliferating cancer cells by nucleolar protein staining.

Supplier: Abcam

Essential polyunsaturated fatty acid. PPAR activator. Induces apoptosis. Augments cellular oxidant status and induces mitochondrial dysfunction. Modulates the infla mMatory process and regulates neutrophil function. Stimulates thromboxanes and prostaglandin production. Shows antithrombotic effects in vivo. Orally active.

Supplier: Abcam

Monochlorobimane is a cell-permeant probe for quantifying glutathione levels in cells. It is essentially nonfluorescent until it reacts with a thiol group. It readily reacts with several low molecular weight thiols, including cysteine, glutathione, N-acetylcysteine, mercaptopurine, peptides and plasma thiols. The glutathione conjugate of monochlorobimane has an excitation/emission maxima ~394/490 nM.

Supplier: Abcam

Anti-p63 antibody [4A4] is a mouse monoclonal antibody designed to detect p63, a transcription factor essential for the development and maintenance of epithelial tissues. Validated for immunohistochemistry (IHC) and reacts with human samples. - Cited in over 150 publications - Trusted by researchers since 2002.