96141 Results for: "Flame Ionization Detector (FID) Supplies"

Supplier: ANTIBODIES.COM

Human IL-17A Matched Antibody Pair Kit includes an unlabeled monoclonal capture antibody, biotin-labeled monoclonal detection antibo dy, Streptavidin-HRP, recombinant human IL-17A ELISA standard, and standard reconstitution buffer. This matched antib 1 * 576 Tests

Supplier: Sartorius

The Vivacon 500 PCR Grade units have been treated with a dual-cycle ethylene oxide (ETO) gas process to ensure they are sterile to a safety assurance level of 106 and free of detectable human genomic DNA contamination. Tests were performed with a qP 1 * 100 items

Supplier: Biotium

Near-infrared CF™ dye antibodies are affinity-purified antibodies labeled with near-infrared fluorescent CF™750 or CF™770, two members of the novel CF™ dye series developed by Biotium for labeling proteins and other biomolecules. CF™ dyes are designed to offer advantages in brightness, photostability, and/or specificity compared to other commercial dyes, and are available in colors spanning the visible, far-red, and near-infrared spectra.

Supplier: Biotium

Near-infrared CF™ dye antibodies are affinity-purified antibodies labeled with near-infrared fluorescent CF™750 or CF™770, two members of the novel CF™ dye series developed by Biotium for labeling proteins and other biomolecules. CF™ dyes are designed to offer advantages in brightness, photostability, and/or specificity compared to other commercial dyes, and are available in colors spanning the visible, far-red, and near-infrared spectra.

Supplier: Biotium

Near-infrared CF™ dye antibodies are affinity-purified antibodies labeled with near-infrared fluorescent CF™750 or CF™770, two members of the novel CF™ dye series developed by Biotium for labeling proteins and other biomolecules. CF™ dyes are designed to offer advantages in brightness, photostability, and/or specificity compared to other commercial dyes, and are available in colors spanning the visible, far-red, and near-infrared spectra.

Supplier: ProSci Inc.

MAb MTC754 recognises a 60 kDa antigen associated with the mitochondria in cells. It is a part of a new panel of reagents, which recognises subcellular organelles or compartments of cells. These markers may be useful in identification of these organelles in cells, tissues, and biochemical preparations. MAb MTC754 recognises an antigen associated with the mitochondria in cells from a wide variety of animals including insects and bacteria. It can be used to stain the mitochondria in cell or tissue preparations and can be used as a mitochondrial marker in subcellular fractions. It produces a spaghetti-like pattern in normal and malignant cells and may be used to stain mitochondria of cells in frozen tissue sections. It can also be used with paraformaldehyde fixed frozen tissue or cell preparations.

Supplier: ProSci Inc.

Recognises a cluster of proteins between 70-80 kDa, identified as tyrosinase. Occasionally a minor band at 55 kDa is also detected. This mAb shows no cross-reaction with MAGE-1 and tyrosinase-related protein 1, TRP-1/gp75. Tyrosinase is a copper-containing metalloglycoprotein that catalyses several steps in the melanin pigment biosynthetic pathway; the hydroxylation of tyrosine to L-3,4-dihydroxy-phenylalanine (dopa), and the subsequent oxidation of dopa to dopaquinone. Mutations of the tyrosinase gene occur in various forms of albinism. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. Staining of melanomas with this mAb shows tyrosinase in melanotic as well as amelanotic variants. This mAb is a useful marker for melanocytes and melanomas.

Supplier: ProSci Inc.

This mAb is specific to SUMO-1 and shows no cross-reaction with either SUMO2 or SUMO3. The small ubiquitin-related modifier (SUMO) proteins, which include SUMO1, SUMO2 and SUMO3, belong to the ubiquitin-like protein family. Like ubiquitin, the SUMO proteins are synthesised is precursor proteins that undergo processing before conjugation to target proteins. Also, both utilize the E1, E2, and E3 cascade enzymes for conjugation. However, SUMO and ubiquitin differ with respect to targeting. Ubiquitination predominantly targets proteins for degradation, whereas sumoylation targets proteins to a variety of cellular processing, including nuclear transport, transcriptional regulation, apoptosis and protein stability. The unconjugated SUMO1 protein localizes to the nuclear membrane.

Supplier: ProSci Inc.

Estrogen receptor (ER) is an important regulator of growth and differentiation in the mammary gland. It is found in two forms, alpha and beta. Both forms are widely expressed, however, alpha is the predominant form in endometrium and breast cancer cells, and beta is more highly expressed in brain, kidney, heart, lung and bone. Activated Estrogen receptor dimerizes and forms both homo- and heterodimers. ER contains five domains: A-F. The A and B domain are able to weakly activate ER in the absence of ligand. The C domain binds DNA and the E domain contains the ligand binding site. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy. This antibody is specific to estrogen receptor alpha and shows minimal cross-reaction with other members of the family.

Supplier: ProSci Inc.

Smooth muscle myosin heavy chain (SM-MHC) is a cytoplasmic structural protein, which is a major component of the contractile apparatus in smooth muscle cells. Expression of smooth muscle myosin is developmentally regulated, appearing early in smooth muscle development, and is specific for smooth muscle development. Two isoforms of smooth muscle myosin heavy chain have been identified, designated MHC-1 and MHC-2. The antibody may be useful for the study of breast tumors as the presence of an intact layer of myoepithelial cells is an important feature, which may distinguish benign breast lesions and carcinoma in situ from invasive tumors.

Supplier: ProSci Inc.

Cytokeratin-7 (CK7) is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. CK7 is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. It is found in simple glandular epithelia, and in transitional epithelium. Epithelial cells of the lung and breast both contain CK7, but some other glandular epithelia, such as those of the colon and prostate, do not. Because the protein is found in both healthy and neoplastic cells, antibodies to CK7 can be used in immunohistochemistry to distinguish ovarian and transitional cell carcinomas from colonic and prostate cancers, respectively. It is commonly used together with CK20 when making such diagnoses. [Wiki].

Supplier: ProSci Inc.

CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterised by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45RB is expressed on mature B-lymphocytes and the majority of lymphomas and leukemias of B-cell origin. This antigen is also expressed on the surface of cells of myeloid lineage.

Supplier: ProSci Inc.

The c-Myc protein is a transcription factor, which is encoded by the c-Myc gene on human chromosome 8q24. c-Myc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation, differentiation, apoptosis and cell cycle progression. The phosphorylation of c-Myc has been investigated and previous studies have suggested a functional association between phosphorylation at Thr58/Ser62 by glycogen synthase kinase 3, cyclin dependent kinase, ERK2 and C-Jun N terminal Kinase (JNK) in cell proliferation and cell cycle regulation. Studies also have shown that c-Myc is essential for tumor cell development in vasculogenesis and angiogenesis that distribute blood throughout the cells, and which brought extensive attention in the development of new therapeutic approach for cancer treatment.

Supplier: IKA

Extremely powerful laboratory stirrers for highly viscous applications and intensive mixing of quantities up to 100 L (H₂O). Units automatically adjust the speed through microprocessor controlled technology within the speed range of speed range of 6 to 2000 min⁻¹ or 4 to 530 min⁻¹ (P4 models), all models have two speed ranges. Safety circuits ensure automatic cut off in anti-stall or overload conditions. The actual shaft speed and preset speed are constantly monitored and variations are adjusted automatically. This guarantees a constant speed even with changes in sample viscosities.

Supplier: ProSci Inc.

Signaling adapter that couples activated growth factor receptors to signaling pathway. Isoform p46Shc and isoform p52Shc, once phosphorylated, couple activated receptor tyrosine kinases to Ras via the recruitment of the GRB2/SOS complex and are implicated in the cytoplasmic propagation of mitogenic signals. Isoform p46Shc and isoform p52Shc may thus function as initiators of the Ras signaling cascade in various non-neuronal systems. Isoform p66Shc does not mediate Ras activation, but is involved in signal transduction pathways that regulate the cellular response to oxidative stress and life span. Isoform p66Shc acts as a downstream target of the tumor suppressor p53 and is indispensable for the ability of stress-activated p53 to induce elevation of intracellular oxidants, cytochrome c release and apoptosis. The expression of isoform p66Shc has been correlated with life span

Supplier: ProSci Inc.

Myc proto-oncogene encodes nuclear DNA-binding phosphoproteins that are involved in the regulation of gene expression and DNA replication during cell growth and differentiation. Myc encodes a protein of 65 kDa which is expressed in almost all normal and transformed cells. The expression correlates with the proliferation state of the cells. Transcription is repressed in quiescent or terminally differentiated cells. Expression of Myc is generally induced after mitogenic stimulation of cells or serum induction. Myc therefore is an important positive regulator of cell growth and proliferation. Myc has been demonstrated also to be a potent inducer of apoptosis when expressed in the absence of serum or growth factors. Apoptosis may serve also as a protective mechanism to prevent tumorigenicity elicited by deregulated Myc expression. Sequences of the Myc oncogene have been highly conserved throughout evolution, from Drosophila to vertebrates

Supplier: Lovibond Tintometer

A series of spectrophotometric colorimeters for colour grading of optically clear samples. Each version of the PFXi 195 includes a selection of standard colour scales that is used in a specific industry sector. Additional scales can be added, at the time of order or remotely, as optional upgrades, to provide the flexibility to meet individual requirements. Results can also be displayed in terms of spectral data and CIE values. For product types that are incompatible with the standard colour scales, the PFXi 195 software allows the users to build up a customised scale from a series of reference samples, and then to obtain the closest match to the stored reference.

Supplier: ANTIBODIES.COM

Monkey IL-17A Matched Antibody Pair Kit includes an unlabeled monoclonal capture antibody, biotin-labeled monoclonal detection antib ody, Streptavidin-AP, recombinant human IL-17A ELISA standard, and standard reconstitution buffer. This matched antib 1 * 576 Tests

Supplier: ANTIBODIES.COM

Mouse IL-17A Matched Antibody Pair Kit includes an unlabeled monoclonal capture antibody, biotin-labeled monoclonal detection antibo dy, Streptavidin-HRP, recombinant mouse IL-17A ELISA standard, and standard reconstitution buffer. This matched antib 1 * 1.920 Tests

Supplier: ANTIBODIES.COM

Monkey IL-13 Matched Antibody Pair Kit includes an unlabeled monoclonal capture antibody, biotin-labeled monoclonal detection antibo dy, Streptavidin-HRP, recombinant human IL-13 ELISA standard, and standard reconstitution buffer. This matched antibo 1 * 576 Tests

Supplier: ANTIBODIES.COM

Sheep IL-17A Matched Antibody Pair Kit includes an unlabeled monoclonal capture antibody, biotin-labeled monoclonal detection antibo dy, Streptavidin-AP, recombinant bovine IL-17A ELISA standard, and standard reconstitution buffer. This matched antib 1 * 576 Tests

Supplier: ANTIBODIES.COM

Human IL-17F Matched Antibody Pair Kit includes an unlabeled monoclonal capture antibody, biotin-labeled monoclonal detection antibo dy, Streptavidin-AP, recombinant human IL-17F ELISA standard, and standard reconstitution buffer. This matched antibo 1 * 1.920 Tests

Supplier: ANTIBODIES.COM

Human GM-CSF Matched Antibody Pair Kit includes an unlabeled monoclonal capture antibody, biotin-labeled monoclonal detection antibo dy, Streptavidin-AP, recombinant human GM-CSF ELISA standard, and standard reconstitution buffer. This matched antibo 1 * 1.920 Tests

Supplier: ANTIBODIES.COM

Sheep IL-17A Matched Antibody Pair Kit includes an unlabeled monoclonal capture antibody, biotin-labeled monoclonal detection antibo dy, Streptavidin-HRP, recombinant bovine IL-17A ELISA standard, and standard reconstitution buffer. This matched anti 1 * 1.920 Tests

Supplier: ANTIBODIES.COM

Bovine IL-17A Matched Antibody Pair Kit includes an unlabeled monoclonal capture antibody, biotin-labeled monoclonal detection antib ody, Streptavidin-HRP, recombinant bovine IL-17A ELISA standard, and standard reconstitution buffer. This matched ant 1 * 1.920 Tests

Supplier: ANTIBODIES.COM

Monkey IL-13 Matched Antibody Pair Kit includes an unlabeled monoclonal capture antibody, biotin-labeled monoclonal detection antibo dy, Streptavidin-AP, recombinant human IL-13 ELISA standard, and standard reconstitution buffer. This matched antibod 1 * 1.920 Tests

Supplier: ANTIBODIES.COM

Human GM-CSF Matched Antibody Pair Kit includes an unlabeled monoclonal capture antibody, biotin-labeled monoclonal detection antibo dy, Streptavidin-HRP, recombinant human GM-CSF ELISA standard, and standard reconstitution buffer. This matched antib 1 * 576 Tests

Supplier: ProSci Inc.

Cyclins, regulatory subunits which associate with kinases, control many of the important steps in cell cycle progression. The Cdc2 kinase (p34Cdc2) exhibits kinase activity in vitro and exists in a complex with both cyclin B and a protein homologous to p13SUC1. Cdc2 kinase is the active subunit of the M phase promoting factor (MPF) and the M phase-specific Histone H1 kinase. The p34Cdc2/cyclin B complex is required for the G2 to M transition. An additional cell cycle-dependent protein kinase, termed p55cdc, exhibits a high degree of homology with the S. cerevisiae proteins Cdc20 and Cdc4. The p55cdc transcript is readily detectable in a variety of cultured cell lines in growth phase, but disappears when cell growth is chemically arrested.

Supplier: ProSci Inc.

Actin participates in many important cellular processes, including muscle contraction, cell motility, cell division and cytokinesis, vesicle and organelle movement, cell signaling, and the establishment and maintenance of cell junctions and cell shape. An actin protein's mass is roughly 42- kDa and it is the monomeric subunit of two types of filaments in cells: microfilaments, one of the three major components of the cytoskeleton, and thin filaments, part of the contractile apparatus in muscle cells. It can be present as either a free monomer called G-actin (globular) or as part of a linear polymer microfilament called F-actin (filamentous), both of which are essential for such important cellular functions as the mobility and contraction of cells during cell division. [Wiki]

This antibody recognises actin of skeletal, cardiac, and smooth muscle cells.

Supplier: ProSci Inc.

Recognises a carbohydrate determinant of Gal 1-3(Fuc 1-4) GlcNAc which is blood group antigen Lewis A. It is present primarily on epithelial cells such as colon and kidneys. In the tumors and dedifferentiated tissues, decrease of Lewis A antigen was observed. Lewis A (type 1 chain) is expressed in colonic epithelial cells and may be useful for detection of gastrointestinal tumors, pancreatic cancer, and colorectal tumors. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.