Anti-MUC1 (CD227) Mouse Monoclonal Antibody [clone: 16A]

Catalog # STMC60155

Supplier: STEMCELL Technologies

Catalog # STMC60155

Supplier: STEMCELL Technologies

Specifications

Antigen name:
MUC1 (CD227)
Clonality:
Monoclonal
Clone:
16A
Conjugation:
Unconjugated
Host:
Mouse
Isotype:
IgG1 lambda
Reactivity:
Human
Gene ID:
4582
Pk:
100 µG

Specifications

About this item

Mouse monoclonal IgG1 antibody against human MUC1 (CD227), unconjugated.

Airway cells

The 16A antibody reacts with human MUC1, a large (>250 kDa) heavily glycosylated type 1 transmembrane protein expressed on the surface of most glandular and ductal epithelial cells and a variety of hematopoietic cells. A characteristic feature of the MUC1 glycoprotein is a core domain composed of a variable number of tandem repeats and multiple oligosaccharide side chains. Because the extracellular portion of MUC1 can extend beyond most cell surface proteins, it is thought to play a role in cell-cell and cell-substrate adhesion. The protein is highly expressed by a majority of human adenocarcinomas and is associated with a poor prognosis. In the mammary gland, MUC1 is localized on the apical plasma membrane of luminal epithelial cells. The clone 16A antibody has a higher affinity for the glycosylated form of MUC1.

Caution: Product restrictions: (i) Customer shall not make products or any portion of them in any way, shape or form, including as a component of another product available for the purpose of further resale or alter or remove the Product label and the Supplier’s mark of origin without express written permission of Supplier and (ii) Customer is familiar with Supplier’s restrictions on the use of the products and shall use the products in compliance with such restrictions and the applicable Supplier Product Information sheet (collectively, the 'Product Restrictions').

Type:
Antigen: MUC1 (CD227)
Clonality: Monoclonal
Clone: 16A
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1 lambda
Reactivity: Human