Anti-CD34 Mouse Monoclonal Antibody [clone: 563] (PE)

Catalog # STMC60119PE

Supplier: STEMCELL Technologies

Catalog # STMC60119PE

Supplier: STEMCELL Technologies

Specifications

Antigen name:
CD34
Clonality:
Monoclonal
Clone:
563
Conjugation:
PE (Phycoerythrin)
Host:
Mouse
Isotype:
IgG1 kappa
Reactivity:
Cynomolgus monkey,
Rhesus monkey,
Human
Gene ID:
947
Pk:
50 Tests

Specifications

About this item

Mouse monoclonal IgG1 antibody against human, rhesus, cynomolgus CD34, PE-conjugated.

Hematopoietic stem
Progenitor cells

CD34 is an ~105 - 120 kDa type 1 transmembrane glycoprotein expressed on the surface of most human hematopoietic stem and progenitor cells (HSPCs), as well as on endothelial cells and some tumor cell lines. The frequency of CD34+ cells is low in bone marrow (1 - 4%), cord blood (~1%), and peripheral blood (<0,1%). CD34 is used to identify and isolate HSPCs, including those capable of reconstituting hematopoiesis after transplantation. Distinct epitope groups have been assigned to CD34 based on differences in the structure of carbohydrate groups, which affects their sensitivity to enzymatic cleavage. The 563 antibody recognises a class III epitope (resistant to neuraminidase and O-glycoprotease). Clone 563 also cross-reacts with CD34+ cells of rhesus, cynomolgus, and pigtailed macaques, but not baboons.

Caution: Product restrictions: (i) Customer shall not make products or any portion of them in any way, shape or form, including as a component of another product available for the purpose of further resale or alter or remove the Product label and the Supplier’s mark of origin without express written permission of Supplier and (ii) Customer is familiar with Supplier’s restrictions on the use of the products and shall use the products in compliance with such restrictions and the applicable Supplier Product Information sheet (collectively, the 'Product Restrictions').

Type:
Antigen: CD34
Clonality: Monoclonal
Clone: 563
Conjugation: PE
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Cynomolgus monkey, Human, Rhesus monkey