Anti-HLA-DR Mouse Monoclonal Antibody [clone: LN3] (PE)

: STEMCELL Technologies

Anti-HLA-DR Mouse Monoclonal Antibody [clone: LN3] (PE)

: STEMCELL Technologies

Mouse monoclonal IgG2b antibody against human, rhesus HLA-DR, PE-conjugated.

B cells
Dendritic cells
Macrophages
Monocytes
Other
T cells

The LN3 antibody reacts with the HLA-DR antigen, a major histocompatibility complex (MHC) class II receptor encoded within the human leukocyte antigen (HLA) complex on chromosome 6. HLA-DR is a heterodimeric transmembrane glycoprotein comprising non-covalently associated α (36 kDa) and β (27 kDa) subunits. MHC class II plays a central role in the presentation of antigen-derived peptides to CD4+ T cells, along with CD3/TCR and CD4. HLA-DR is primarily expressed on the surface of antigen-presenting cells, including B cells, dendritic cells, monocytes, macrophages, thymic epithelial cells, and activated T and natural (NK) cells. The LN3 antibody binds to an extracellular epitope that reportedly resides within the HLA-BR1 subunit of HLA-DR.

: Product restrictions: (i) Customer shall not make products or any portion of them in any way, shape or form, including as a component of another product available for the purpose of further resale or alter or remove the Product label and the Supplier’s mark of origin without express written permission of Supplier and (ii) Customer is familiar with Supplier’s restrictions on the use of the products and shall use the products in compliance with such restrictions and the applicable Supplier Product Information sheet (collectively, the 'Product Restrictions').

Type:
Antigen: HLA-DR
Clonality: Monoclonal
Clone: LN3
Conjugation: PE
Epitope:
Host: Mouse
Isotype: IgG2b kappa
Reactivity: Human, Rhesus monkey