Specifications
- Antibody type:Primary
- Antigen name:CTNNA3
- Clonality:Polyclonal
- Conjugation:FITC (Fluorescein Isothiocyanate)
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Western blot:Yes
- Epitope:131-230/895
- Form:Liquid
- Antigen synonyms:MGC75041|Catenin alpha 3|OTTMUSP00000028119|Alpha T-catenin|CTNNA3|OTTHUMP00000019684|4930429L08Rik|Alpha T catenin|MGC26194|CTNA3_HUMAN|Catenin alpha-3|Catna3|OTTMUSP00000028120|Cadherin-associated protein|Cadherin associated protein|RP11-433J16.1|Alpha catenin like protein|VR22|4933408A16
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol.
- Molecular weight:100 kDa
- Storage temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human CTNNA3
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
Specifications
About this item
The catenins are ubiquitously expressed, cytoplasmic proteins that associate with E-cadherin at cellular junctions. Catenin/cadherin complexes play an important role in mediating cellular adhesion. alpha T-catenin, also referred to as VR22, is a 895-amino acid protein that is most abundantally expressed in cardiomyocytes and in the peritubular myoid cells of the testis. alpha T-catenin binds to alpha E-catenin as well as to beta-catenin, and it functions to inhibit Wnt signaling. CTNNA3, the gene that encodes for alpha-T-catenin, is located on chromosome 10, and mutations in this gene show a strong correlation to late-onset Alzheimer's disease (LOAD) as well as to dilated cardiomyopathy.
Type: Primary
Antigen: CTNNA3
Clonality: Polyclonal
Clone:
Conjugation: FITC
Public Immunogen Range: 131-230/895
Host: Rabbit
Isotype: IgG
Reactivity: