Anti-BECN1 Rabbit Polyclonal Antibody
ENZOADI905721100
- Antibody type:Primary
- Antigen name:Beclin 1
- Antigen symbol:BECN1
- Clonality:Polyclonal
- Host:Rabbit
- ImmunoChemistry:Yes
- Western blot:Yes
- Seq:02
- Form:Liquid. In PBS containing 0,02% sodium azide.
- Antigen synonyms:Coiled-coil myosin-like BCL2-interacting protein|APG 6|VPS30|Beclin1 autophagy|ATG6|CTIP-1 COUP-TF interacting protein 1|Protein GT197
- Purification:Peptide affinity purified
- Pk:100 µG
Beclin-1 is a coiled-coil Bcl-2-interacting protein that functions in autophagy, the process of bulk degradation of cellular proteins. Beclin-1 is homologous to the yeast autophagy gene apg6, and is expressed at reduced levels in human breast carcinoma, suggesting that defects in autophagy proteins may contribute to the development or progression of tumors. Bcl-2 can inhibit Beclin-1-dependent autophagy in yeast and mammalian cells, suggesting that Bcl-2 functions as both an anti-autophagic and anti-apoptotic protein.
- For Immunohistochemistry, Western Blot
Recognizes human, mouse and rat Beclin-1. Detects a band of ~57kDa by Western blot.
Type: Primary
Antigen: BECN1
Clonality: Polyclonal
Clone:
Conjugation:
Epitope:
Host: Rabbit
Isotype:
Reactivity: Human