1924 Results for: "TMC HALLCREST"

Supplier: ENZO LIFE SCIENCES

Substrate for caspase-1 and -5

Supplier: ENZO LIFE SCIENCES

PP2A inhibitor

Supplier: ENZO LIFE SCIENCES

Reversible inhibitor of DNA polymerase a and d

Supplier: ENZO LIFE SCIENCES

Acetyl-CoA inhibitor

Supplier: ENZO LIFE SCIENCES

Cell permeable, potent and selective p38 MAP kinase inhibitor (IC50=30 nM). Inhibits p38α and ß, but not γ and δ isoforms. Does not inhibit ERK2 or other members of the MAP kinase family or their upstream activators. A useful tool for dissecting the role of p38 in signaling pathways. Induces apoptosis.

Supplier: ENZO LIFE SCIENCES

PKG inhibitor

Supplier: ENZO LIFE SCIENCES

Inhibitor of cAMP- and cGMP-dependent protein kinase (PKA, Ki=4.3µM and PKG, Ki=3.8µM), protein kinase C (PKC, Ki=47µM), casein kinase I and II, and myosin light chain kinase (MLCK, Ki=7.4µM).

Supplier: ENZO LIFE SCIENCES

Potent GABAA receptor agonist.

Supplier: ENZO LIFE SCIENCES

Ca²⁺ channel blocker

Supplier: US Biological

Anti-TMC6 Rabbit Polyclonal Antibody (APC (Allophycocyanin))

Supplier: US Biological

Anti-TEC Rabbit Polyclonal Antibody (PE (Phycoerythrin))

Supplier: AAT BIOQUEST

D-VLK-AMC is a sensitive, highly specific fluorescent substrate for plasmin.

Supplier: ENZO LIFE SCIENCES

Topoisomerase inhibitor

Supplier: ENZO LIFE SCIENCES

Mycotoxin. Nephrotoxic.

Supplier: ENZO LIFE SCIENCES

K⁺ channel activator.

Supplier: ENZO LIFE SCIENCES

Potent inhibitor of farnesyltransferase in isolated enzyme assays (IC50=55nM) but is inactive in whole cells. Inhibition of farnesyltransferase is selective over geranylgeranyltransferase I and II (IC50=92µM and 34µM respectively).

Supplier: ENZO LIFE SCIENCES

AP-1 inhibitor

Supplier: ENZO LIFE SCIENCES

Estrogen receptor ligand.

Supplier: ENZO LIFE SCIENCES

Mycotoxin

Supplier: Apollo Scientific

Used for derivatization, TLC & HPLC separation, & fluorometric analysis of a wide range of naturally occuring acids, including bile & thromboxane B2

Supplier: ENZO LIFE SCIENCES

Negative control for C8 ceramide.

Supplier: ENZO LIFE SCIENCES

Common component of cell membranes, often as phosphatidyl conjugates. Is a potent (IC50=1-3 µM) and selective inhibitor of protein kinase C. Inhibition is competitive with diacylglycerol, phorbol dibutyrate and Ca2+ and it also inhibits PKC activation by other lipids. It acts on an equimolar basis with 1,2-dioleoylglycerol and does not affect other kinases such as MLCK and PKA. It is active in intact cells and has been identified as an endogenous constituent in HL-60 cells, neutrophils, rat liver, and brain and mouse tissues. Other activities include inhibition of phosphatidate phosphohydrolase, Na+,K+-ATPase, CTP:phosphocholine cytidylyltransferase, calmodulin-dependent enzymes, binding of factor VII to tissue factor, binding of thyrotropin releasing hormone to its receptor and activation of EGF receptor kinase, phospholipase D and casein kinase II.

Supplier: ENZO LIFE SCIENCES

A highly potent, cell-permeable inhibitor of cathepsin K (IC50=51 nM).

Supplier: ENZO LIFE SCIENCES

HNMPA-(AM)3 is a cell-permeable analog of HNMPA. It inhibits insulin receptor tyrosine kinase activity (IC50=100 µM) and insulin-stimulated glucose oxidation in isolated rat adipocytes (IC50=10 µM). It has no effect on PKA (at concs. up to 1 mM) or PKC (at concs. up to 420 µM). Inhibits both serine and tyrosine autophosphorylation by the human insulin receptor. Does not affect protein kinase C (PKC) or cAMP-dependent protein kinase (PKA).

Supplier: ENZO LIFE SCIENCES

Inhibits Rho kinase (ROCK; Ki=0.33μM). Selective protein kinase A and G inhibitor (both Ki’s = 1.6μM). Inhibits agonist-induced activation of NADPH oxidase in human neutrophils (IC50=15μM). Inhibitor of myosin light chain kinase and Ca2+/calmodulin-dependent protein kinase II. Inhibits translocation of PKCβI, PKCβII and PKCζ. Cell permeable Ca2+ antagonist with antivasospastic properties.

Supplier: ENZO LIFE SCIENCES

Member of the tyrphostin family of tyrosine kinase inhibitors. Selective inhibitor of the PDGF receptor kinase (IC50=20µM) vs. the EGF receptor kinase (IC50=820µM). Inhibits PDGF-induced mitogenesis in human bone marrow fibroblasts.

Supplier: ENZO LIFE SCIENCES

LPA receptor ligand

Supplier: ENZO LIFE SCIENCES

ATPase inhibitor

Supplier: ENZO LIFE SCIENCES

Retinoic acid analog which acts as a selective RARα agonist with no affinity for RXRs. Induces differentiation in leukemia cell lines and inhibits angiogenesis in chick embryos.

Supplier: ENZO LIFE SCIENCES

Monoamine oxidase inhibitor