58748 Results for: "Cayman Chemical"

Imipenem is an intravenous β-lactam antibiotic effective against a wide range of Gram-positive and Gram-negative bacteria (MICs range from 0,5 - 2 µg/ml for E. cloacae and P. aeruginosa), including several multi-drug resistant bacterial species. Imipenem acts by interfering with bacterial cell wall synthesis.

Expand 4 Items

Paroxetine hydrochloride ≥98%

Supplier: Cayman Chemical

Paroxetine is a phenylpiperidine derivative that potently and selectively inhibits the reuptake of serotonin, blocking the human serotonin transporter with a Ki value of 0,72 nM.

Expand 4 Items

Raltegravir potassium salt ≥98%, crystalline solid

Supplier: Cayman Chemical

Raltegravir is a potent, selective, and orally bioavailable inhibitor of HIV integrase (IC50 = 15 nM).

Expand 4 Items

Apixaban ≥98%, crystalline solid

Supplier: Cayman Chemical

Apixaban is an orally bioavailable, selective inhibitor of both free and prothrombinase-bound factor Xa (K_is = 0.8 nM).

Expand 4 Items

Arachidonic Acid 1,2,3,4,5-¹³C ≥95%

Supplier: Cayman Chemical

Arachidonic acid (Item No. 90010) is an essential fatty acid and a precursor for all prostaglandins, thromboxanes, and leukotrienes.

Expand 4 Items

MitoCheck® Complex I Activity Assay Kit

Supplier: Cayman Chemical

A complete system for quantifying complex I inhibition.

Expand 1 Items

Cyclic AMP Select ELISA Kit

Supplier: Cayman Chemical

For direct quantification of cAMP from a variety of biological samples.

Expand 2 Items

α-Hydroxy-o-tolyl-β-D-glucopyranoside

Supplier: Cayman Chemical

Salicin is an alcoholic β-glucoside derived from willow bark that produces anti-inflammatory (including analgesic and antipyretic) effects very similar to that of aspirin. It acts as a non-selective COX inhibitor, exhibiting IC50 values >100 µM for COX-1 and COX-2.

Expand 4 Items

2-Oleoyl Glycerol solution ≥98% in ethanol

Supplier: Cayman Chemical

2-Oleoyl glycerol (2-OG) is a natural monoacylglycerol with an 18:1 oleoyl group at the sn-2 position of glycerol. 2-OG, like 2-arachidonoyl glycerol (2-AG), is metabolized by monoacylglycerol lipase, but, unlike 2-AG, it is not metabolized by cyclooxygenases or lipoxygenases. 2-OG is an agonist of GPR119 (EC₅₀ = 2.5 µM), stimulating the release of glucagon-like peptide-1 from intestinal L-cells.

Expand 4 Items

Virginiamycin complex ≥95%

Supplier: Cayman Chemical

Virginiamycin complex is a complex containing two streptogramin antibiotics, virginiamycin M1 (75%) and virginiamycin S1 (25%), produced by S. virginiae.

Expand 3 Items

Substance P ELISA kit

Supplier: Cayman Chemical

ELISA kit for the measurement of Substance P.

Expand 4 Items

Green CMFDA ≥95% fluorescent dye

Supplier: Cayman Chemical

Green CMFDA is a cell-permeable fluorescent probe that freely enters living cells, where it is transformed into a cell-impermeable, soluble, fluorescent compound. The resulting molecule does not affect cell viability or proliferation and stably fluoresces for at least 72 hours, allowing for its use in cell tracking. It is also transferred to daughter cells.

Expand 3 Items

Malonyl coenzyme A lithium salt ≥90%

Supplier: Cayman Chemical

Malonyl-CoA is formed by acetyl-CoA carboxylase-mediated carboxylation of acetyl-CoA. Fatty acid synthase catalyzes the NADPH-dependent condensation of malonyl-CoA and acetyl-CoA to produce palmitate. Proliferating human cancer cells upregulate this fatty acid synthesis pathway as a strategy for survival. High levels of malonyl-CoA, achieved through fatty acid synthase inhibition, proposed to contribute to cancer cell apoptosis.

Expand 4 Items

Ribavirin ≥95%, crystalline solid

Supplier: Cayman Chemical

Ribavirin is a guanosine analog with antiviral properties against DNA and RNA viruses, including respiratory syncytial virus, hepatitis C, and influenza.

Expand 4 Items

Bilirubin conjugate, sodium salt

Supplier: Cayman Chemical

Bilirubin conjugate is a stable, water-soluble ditaurate derivative of bilirubin meant to mimic endogenous bilirubin glucuronide derivatives.

Expand 4 Items

Standards for saturated/monounsaturated fatty acids, LC-MS mixture

Supplier: Cayman Chemical

Saturated or monounsaturated fatty acid LC-MS mixture contains various saturated or unsaturated fatty acids. The mixture is supplied in an amber ampule in which the headspace has been purged with argon to prevent lipid oxidation. This product has been designed for direct use in LC-MS applications.