58750 Results for: "Cayman Chemical"

Sphingosine kinase isoforms, SPHK 1 and SPHK 2, catalyse the phosphorylation of sphingosine to sphingosine-1-phosphate (S1P). S1P exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis. Sphingosine kinase inhibitor 2 (SPHK I₂) is a potent, selective inhibitor of SPHK 1 with anti-proliferative activity.

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Treprostinil ≥98%

Supplier: Cayman Chemical

Treprostinil is a stable analog of prostacyclin that is used clinically for the treatment of PPH under the trade name Remodulin™. The structural modifications in treprostinil compared to prostacyclin increase the plasma half-life from 2 minutes to 34 and 85 minutes for intravenous and subcutaneous infusion of the drug, respectively

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Indole-4-carbaldehyd

Supplier: Cayman Chemical

Indole-4-carbaldehyd

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8-Bromoisoquinoline

Supplier: Cayman Chemical

8-Bromoisoquinoline

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Stearic acid

Supplier: Cayman Chemical

Stearic acid

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Human Recombinant 15-Lipoxygenase-2 (from E. coli)

Supplier: Cayman Chemical

Two types of 15-lipoxygenase (15-LO) have been discovered and characterised, both of which metabolise arachidonic acid (AA) to produce 15(S)-hydroxyeicosatetraenoic acid (15(S)-HETE). 15-LO-1 oxygenates AA at both C-15 and C-12, whereas 15-LO-2 exclusively oxygenates C-15 of AA. Human 15-LO-2 has a molecular mass of approximately 76 kDa and exhibits approximately 40% identity to the reticulocyte 15-LO-1.2,3 expression of 15-LO-2 appears to be restricted to prostate, lung, skin, and cornea and may play a role in the normal development of these tissues.

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5-Bromo-1-tetralone

Supplier: Cayman Chemical

5-Bromo-1-tetralone

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cis,cis,cis-13,16,19-Docosatrienoic acid

Supplier: Cayman Chemical

cis,cis,cis-13,16,19-Docosatrienoic acid

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Anti-PGIS Rabbit Polyclonal Antibody

Supplier: Cayman Chemical

Anti-PGIS Rabbit Polyclonal Antibody

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Rivaroxaban

Supplier: Cayman Chemical

Rivaroxaban is an orally active, direct inhibitor of Factor Xa (Ki = 0,4 nm), which is a crucial component of the intrinsic and extrinsic pathways of the blood coagulation cascade.

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BAM15 ≥98%, crystalline solid

Supplier: Cayman Chemical

BAM15 is a mitochondrial protonophore uncoupler which increase proton transport into the mitochondrial matrix through an ATP synthase-independent pathway, thereby uncoupling nutrient oxidation from ATP production.

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2-Acetamido-1,3,4,6-tetra-O-acetyl-2-deoxy-β-D-glucopyranose ≥95%

Supplier: Cayman Chemical

β-D-Glucosamine pentaacetate is an N-acetylglucosamine derivative that has been shown to promote hyaluronic acid production.

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Luminol (3-Aminophthalhydrazide) ≥98%

Supplier: Cayman Chemical

Luminol is a cyclic diacyl hydrazide that exhibits chemiluminescence upon oxidation.

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Calcein fluorescent indicator

Supplier: Cayman Chemical

Calcein is a xanthene that is commonly used for the fluorometric determination of calcium in solution. As this form of calcein is not membrane permeable, it can be used in assays that evaluate membrane integrity. Calcein can also be used as a fluorescent indicator for fluoride, iron, and mercury. Excitation and emission maxima for calcein are 494 and 517 nm, respectively.