69789 Results for: "1,5-Difluoro-2-methyl-4-nitrobenzene"

Supplier: GA

Thermal transfer cryogenic labels that will firmly adhere to both ambient and already frozen surfaces (as low as -80 °C) without the need for thawing, cure time, or any other special treatment prior to long-term storage in liquid nitrogen (–196 °C).

Supplier: ProSci Inc.

Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody detects acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins: 67 kDa (CK1); 64 kDa (CK3); 59 kDa (CK4); 58 kDa (CK5); 56 kDa (CK6); 52 kDa (CK8); 56.5 kDa (CK10); 50 kDa (CK14); 50 kDa (CK15); 48 kDa (CK16); 40 kDa (CK19). Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. It is a broad spectrum anti pan-cytokeratin antibody, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It may be useful to characterize the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. This antibody stains cytokeratins present in normal and abnormal human tissues and has high sensitivity in the recognition of epithelial cells and carcinomas.

Supplier: Whatman products (Cytiva)

The Whatman Mini-UniPrep Syringeless Filters combine four products into one syringeless filter solution for efficient chromatography sample preparation for a broad range of applications. They are built for fast and easy high performance liquid chromatography/ultra high performance liquid chromatography sample preparation and analysis.

Supplier: Brand

The Transferpette® S air displacement pipette allows you to work efficiently and ergonomically with both small and large volumes. Due to its perfect ergonomics, the Transferpette® S provides a comfortable grip in any hand position, whether you are right- or left-handed, or have big or small hands.

Supplier: BANDELIN-ELECTRONIC

High-performance ultrasonic cleaning bath with heating for industry, service and maintenance. The welded oscillating tank made of stainless steel V4A (1 4404), 2 mm guarantees maximum durability even with intensive use.

Supplier: VWR Collection

IL 10, IL 23 and IL 56 digital incubators offer an economical and space saving solution for microbiology or haematology applications. The temperature can be freely adjusted in increments of 0,1 °C up to a maximum of 70 °C. Heating elements are incorporated into the housing base and walls to ensure temperature stability and uniformity. The IL 10 is available with a transparent Plexiglas® window to provide full visibility or a painted, opaque Plexiglas® window to protect photosensitive samples. IL 23 and IL 56 come as standard with a transparent Plexiglas® window. The housing and door frame are constructed entirely of epoxy coated mild steel.

Supplier: Thermo Scientific

The SL1/SL1R Plus series centrifuges come standard with an easy-to-use keypad and high contrast LCD display. Quickly and securely swap between 14 unique rotor options with the tool-less Auto-Lock rotor exchange. This compact centrifuge has a capacity up to 1,6 L and can spin up to 76 × 5/7 ml blood tubes and 16 × 50 ml conical tubes with biocontainment and is ideal for routine applications.

Supplier: Abcam

Angiotensin II ELISA kit is a competitive ELISA assay for the quantitative measurement of Ang II in Human serum, plasma, tissue homogenates and other biological fluids.

Supplier: Thermo Fisher Scientific

Rigid PC frame, thin-walled PP wells. Ultra-rigid 96-well PCR plates with rounded V-bottom wells designed for robotic applications.

Supplier: VWR Collection

The UH5700 UV-Vis-NIR Spectrophotometer is a high-precision benchtop spectrophotometer instrument designed for handling the ultraviolet, visible and near-infrared regions (190 to 3300 nm).

Supplier: Liebherr

Freezers with a spark-free interior specifically for storing explosive and highly flammable substances in laboratories and in the chemical industry.

Supplier: Avantor Fluid Handling

Versatile pumps for accurate fluid delivery – with an intuitive touch-screen interface.

Supplier: Avantor Fluid Handling

Versatile pumps for process applications - with an intuitive touch-screen interface and advanced connectivity. This drive offers a broad flow range, from 0,0006 to 19 LPM, adaptable to a variety of applications and workflows. The drive housing is constructed of 316 stainless steel - IP 66 and NEMA 4X rated for washdown.

Supplier: ProSci Inc.

IL15 is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x (L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis.The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x (L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported.

Supplier: ProSci Inc.

ADAM15 is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling.The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.

Supplier: ProSci Inc.

Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be essential for the biogenesis of COX formation and may function in the hydroxylation of heme O, according to the yeast mutant studies. This protein is predicted to contain 5 transmembrane domains localized in the mitochondrial inner membrane.Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be essential for the biogenesis of COX formation and may function in the hydroxylation of heme O, according to the yeast mutant studies. This protein is predicted to contain 5 transmembrane domains localized in the mitochondrial inner membrane. Alternative splicing of this gene generates several transcript variants diverging in the 3' region including alternate poly A sites. In total, 2 different isoforms are encoded by these variants.

Supplier: SenseAnywhere

This smart probe featuring a digital SenseAnywhere Bus interface has been especially designed for measuring extreme temperatures in liquid substances. Thanks to its hermetic seal made of PFA, better known as Teflon®, the Hermetically Sealed Pt100 Probe has a high level of chemical resistance. The probe is thanks to its PFA insulation waterproof and easy to clean. It can withstand aggressive substances, allowing it to take measurements in virtually all liquid fluids while being constantly submerged. The PT100 element has a Class A accuracy; measurements are provided at a very high accuracy level.

Supplier: Sartorius Balances

These ultra-micro balances from the Cubis® II range are for highly accurate weighing of microgram quantities, there are also models specifically designed for filter weighing applications.

Supplier: MP Biomedicals

SPINeasy DNA Kit for Water is a high-performance water genomic DNA (gDNA) extraction kit based on silica-membrane spin-column technology. This kit enables quick isolation of gDNA from water in less than 30 min. Water samples are processed using our uniquely formulated Lysis Buffer W1 and Lysing Matrix E to effectively lyse various types of cells. Column W1 provided in the kit has high binding capacity and selectivity for gDNA. The combination of components in the kit extracts gDNA of high yield and purity that is ready for downstream analyses such as PCR, restriction digestion and sequencing.

Supplier: EPPENDORF

Eppendorf's twin.tec® 96-well, 150 µl PCR Plates feature a polycarbonate frame and thin-walled polypropylene wells ensuring optimal heat transfer and high rigidity. The SafeCode variants enhance sample identification, while the BioBased options, manufactured using renewable resources, provide an eco-friendly alternative without compromising performance.

Supplier: Merck

Milli-Q® EQ 7008/7016 ultrapure and reverse osmosis (RO, Type 3) water systems are designed to produce consistent ultrapure water quality [resistivity 18,2 MΩ.cm at 25 °C; total organic carbon (TOC) ≤5 ppb] direct from a tap water source. Final ultrapure water quality can be adapted to each user’s specific application requirements. Plus, a range of intelligent design features make it effortless to dispense water as needed and where needed in the lab.

Supplier: VWR Collection

User friendly instrument, with articulated electrode stand and IP 43-rated housing, provides high resolution and accuracy for precise multi-parameter measurements. This meter can either measure pH/mV and conductivity or pH/mV and oxygen simultaneously. Complete with USB output for connection to a computer. GLP compliant.

Supplier: VWR Collection

These tips are made of high quality, 100% pure, virgin medical grade PP. Made in the highest quality moulds, these tips can be used whenever the work demands a higher standard.

Supplier: Brand

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Supplier: Corning

PS, sterile. The Corning® CellSTACK® culture chambers are available in five sizes and with three different surface treatments.

Supplier: KNICK

This explosion-proof, multi-parameter meter has been specially designed for employment in potentially explosive areas. It is suitable for daily routine pH, ORP, conductivity and oxygen measurements. Waterproof according to IP 66/IP 67.

Supplier: Thermo Scientific

Process a range of general-purpose applications including cell culture, microplate, bioproduction, blood separation, and microbiology with the Thermo Scientific™ Multifuge™ X4 Pro centrifuge series featuring new touch screen technology, making daily tasks easier.

Supplier: AGILENT

The RecoverEase DNA isolation kit recovers high-molecular-weight (100 to 500 kb) genomic DNA that is fully hydrated and ready for multiple applications the next day. DNA can be isolated from whole tissues such as liver, spleen, kidney, brain and testes without hazardous and tedious organic extractions or ethanol precipitations. The RecoverEase DNA isolation kit quickly isolates high-molecular-weight genomic DNA from a variety of tissues without organic solvent extractions or ethanol precipitation.

Supplier: Sartorius Balances

The Cubis® II range has a modular design that to allows the customer to choose the components that suit the application area that is of interest. For the customer, this configurable concept delivers quality weighing, together with a high degree of flexibility, without having to invest in expensive equipment that has features that may never be required.

Supplier: STEMCELL Technologies

Thymus-expressed chemokine (TECK), or CCL25, is a member of the CC family of chemokines that regulates the movement of lymphocytes in the thymus and in the small intestine. TECK induces chemoattraction by binding the chemokine receptor CCR9, which is expressed on immature pre-T cells and thymocytes (Youn et al.; Uehara et al.). In the thymus, TECK is produced by stromal cells, whereas in the small intestine TECK is primarily produced by epithelial cells (Vicari et al.; Bowman et al.; Kunkel et al.). CCR9 is a G protein-coupled receptor and is expressed on most thymocytes, but not on natural killer cells, monocytes, eosinophils, basophils, and neutrophils (Wu et al). In Jurkat cells, binding of TECK to CCL9 has been shown to increase levels of intracellular calcium (Cheng-Rong et al). TECK/CCR9 signaling has also been linked to many cancers, as these molecules have been shown to mediate anti-apoptotic processes by activating the PI3K/AKT signaling pathway, weakening the effect of cytotoxic T cells by regulating STAT signaling. Additionally, TECK induces metastasis by increasing the expression of MMP2 and MMP9 (Tu et al.).