Anti-CD27 Hamster Monoclonal Antibody [clone: LG.3A10] (PE)

Supplier: STEMCELL Technologies

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Supplier: STEMCELL Technologies

About this item

Hamster (Armenian) monoclonal IgG1 antibody against human, mouse, rat CD27, PE-conjugated.

B cells
Nk cells
Other
T cells

The LG.3A10 antibody reacts with CD27, a 45 - 55 kDa member of the tumor necrosis factor receptor superfamily. CD27 is found on peripheral T cells, memory B cells, and NK cells and in mice has been found on most thymocytes, except CD46-CD8- precursors. CD27 and its ligand CD70 are involved in multiple aspects of T cell biology, including the costimulation and expansion of CD4+ and CD8+ T cells and differentiation to memory CD8+ T cells. CD27 interacts with TRAF family members, resulting in enhanced cellular proliferation and the induction of anti-apoptotic proteins. Additionally, CD27 plays important roles in T cell – B cell interactions and the maturation of effector T cells. The expansion of activated B cells and their differentiation to plasma cells is also reported to be enhanced by CD27.

Caution: Product restrictions: (i) Customer shall not make products or any portion of them in any way, shape or form, including as a component of another product available for the purpose of further resale or alter or remove the Product label and the Supplier’s mark of origin without express written permission of Supplier and (ii) Customer is familiar with Supplier’s restrictions on the use of the products and shall use the products in compliance with such restrictions and the applicable Supplier Product Information sheet (collectively, the 'Product Restrictions').

Type:
Antigen: CD27
Clonality: Monoclonal
Clone: LG.3A10
Conjugation: PE
Epitope:
Host: Hamster
Isotype: IgG1 kappa
Reactivity: Human, Mouse, Rat