- Antibody type:Primary
- Antigen name:ALDH3A2
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 680
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Western blot:Yes
- Epitope:101-200/485
- Form:Liquid
- Antigen synonyms:ALDH10|AL3A2_HUMAN|Aldh3|Ahd 3|Aldehyde dehydrogenase 3|FLJ20851|Ahd 3r|Aldehyde dehydrogenase family 3 member A2|Aldh4r|Ahd3|Aldh4|Microsomal aldehyde dehydrogenase|Aldehyde dehydrogenase family 3, subfamily A2|Aldehyde dehydrogenase 3 family, member A2|msALDH|FALDH|Aldh4 r|SLS|Fatty aldehyde dehydrogenase|Ahd3 r|ALDH3A2|Aldehyde dehydrogenase 10|Aldehyde dehydrogenase, family 3, subfamily A, member 2
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:55 kDa
- Storage temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human ALDH3A2
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
Aldehyde dehydrogenases (ALDHs) mediate the NADP+-dependent oxidation of aldehydes into acids and play an important role in the detoxification of alcohol-derived acetaldehyde, as well as in lipid peroxidation and in the metabolism of corticosteroids, biogenic amines and neurotransmitters. ALDH3A2 (aldehyde dehydrogenase 3 family, member A2), also known as SLS, FALDH or ALDH10, is a 485 amino acid single-pass membrane protein that localizes to the cytoplasmic side of the endoplasmic reticulum and belongs to the aldehyde dehydrogenase family. Expressed in a variety of tissues, including liver, heart, lung, brain, kidney and placenta, ALDH3A2 catalyses the NAD+-dependent oxidation of long-chain aliphatic aldehydes to fatty acids, a process that is necessary for detoxification and lipid metabolism. Defects in the gene encoding ALDH3A2 are the cause of Sjoegren-Larsson syndrome (SLS), an autosomal recessive neurocutaneous disorder characterised by severe mental retardation, seizures and speech defects. Multiple isoforms of ALDH3A2 exist due to alternative splicing events.
Type: Primary
Antigen: ALDH3A2
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 101-200/485
Host: Rabbit
Isotype: IgG
Reactivity: