Agilent ZORBAX® Eclipse XDB-C8 columns provide four bonded phase choices for method development optimisation.

• Long lifetime
• Four selectivity choices for method development optimisation
• Good peak shape for basic, acidic and neutral compounds
• High performance over a wide pH range pH 2 to 9
• Particle sizes available in 1,8, 3,5, 5 and 7 μm for high speed, high resolution, analytical and preparative scale separations

These columns provide good peak shape over a wide pH range (2 to 9) for additional method development flexibility with one family of columns. Eclipse XDB columns can be used for method development at low pH (2 to 3) and the same column can be used for method development in the mid pH (6 to 8) region. In the mid pH region, residual silanols are more active and tailing interactions are more likely. To overcome these interactions, Eclipse XDB columns are extra densely bonded and double end capped through a proprietary process to cover as many active silanols as possible. The result is superior peak shape of basic compounds from pH 2 to 9.