Specifications
- Antigen name:Chromobox Homolog 4
- Antigen symbol:CBX4
- Clonality:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Rabbit
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Western blot:Yes
- Antigen synonyms:Chromobox protein homolog 4|E3 SUMO-protein ligase CBX4|PC2|NBP16|Pc2|CBX4
- Storage buffer:PBS containing 0.02% sodium azide
- Immunogen:CBX4 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human CBX4.
- Tested applications:E, WB, IF
- Purification:Affinity chromatography purified via peptide column
- Size:100 µg
- Pk:100 µG
Specifications
About this item
CBX4 Antibody: Polycomb group (PcG) proteins are chromatin-associated proteins which are important for embryonic and adult stem cell self-renewal and maintenance. At least two distinct human PcG complexes have been identified. Polycomb repressive complex I (PRC1) contains CBX4/Pc2, HPH1 and RING domain-containing proteins (RING1, RING2 and BMI1). CBX4 (Chromobox protein homolog 4 or PC2), which functions as a transcriptional suppressor, is a candidate of KyoT2-binding proteins. It is a E3 SUMO-protein ligase which facilitates SUMO1 conjugation. Depletion of CBX4 results in decreased cellular resistance to ionizing radiation. CBX4 is directly involved in the cellular response to DNA damage.
Type:
Antigen: CBX4
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity: Human, Mouse, Rat