Anti-FANCD2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))
Catalog # BOSSBS-13141R-FITC
Supplier: Bioss
Specifications
- Antibody type:Primary
- Antigen name:Fanconi Anemia Complementation Group D2
- Antigen symbol:FANCD2
- Clonality:Polyclonal
- Conjugation:FITC (Fluorescein Isothiocyanate)
- Host:Rabbit
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Human
- Environmentally Preferable:
- Cross adsorption:No
- Form:liquid
- Gene ID:2177
- Antigen synonyms:FAD|FA4|FANCD|FACD|FA-D2|FAD2
- Modification:phospho-Ser1404
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Storage temperature:Store at 4°C for 12 months
- Concentration:1 μg/μl
- Shipping temperature:4°C
- Purification:Purified by Protein A
- Pk:100 µl
Specifications
About this item
Fanconi Anemia (FANC) is a human autosomal-recessive cancer susceptibility disorder characterized by congenital defects, progressive bone marrow failure, and cellular hypersensitivity to mitomycin C (MMC). The FANC subunit D2 protein is vital for cellular resistance to DNA cross-linking and the arrest of DNA synthesis after ionizing radiation. DNA damage activates the monoubiquitination of FANC D2, targeting nuclear foci containing the BRCA 1 protein.
Recommended Dilutions: IF(IHC-P): 1:50-200
Type: Primary
Antigen: FANCD2
Clonality: Polyclonal
Clone:
Conjugation: FITC (Fluorescein Isothiocyanate)
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human