About this item
This antibody recognizes a glycoprotein of 75 kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). Its epitope spans in aa 1-160 of extracellular domain of NGFR/NTR. NGF-receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. NGF is important for the development, differentiation, and survival of variety of neuronal and non-neuronal cells. Its action is mediated by binding two distinct receptors, the high affinity p140 and low affinity p75.
Type: Primary
Antigen: NGFR
Clonality: Monoclonal
Clone: NGFR5
Conjugation: CF568
Epitope:
Host: Mouse
Reactivity: Baboon, Cat, Ferret, Human, Monkey, Rabbit
Isotype: IgG1, kappa
Specifications
- Catalog No:
- BNC680890-100
- BNC680890-500
- Antigen symbol:
- NGFR
- NGFR
- Antigen name:
- Nerve Growth Factor Receptor
- Nerve Growth Factor Receptor
- Antibody type:
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Conjugation:
- CF® 568
- CF® 568
- Clone:
- Clone NGFR5
- Clone NGFR5
- Reactivity:
- Baboon, Rabbit, Monkey, Ferret, Human, Cat
- Baboon, Rabbit, Monkey, Ferret, Human, Cat
- Host:
- Mouse
- Mouse
- Gene ID:
- 415768 , 681726
- 415768 , 681726
- Isotype:
- IgG1 kappa
- IgG1 kappa
- ImmunoChemistry:
- Yes
- Yes
- ImmunoFluorescence:
- Yes
- Yes
- Concentration:
- 0,1 mg/ml
- 0,1 mg/ml
- Storage buffer:
- PBS/0,1% BSA/0,05% azide
- PBS/0,1% BSA/0,05% azide
Specifications
Supplier: VWR Collection
Supplier: KIMBERLY CLARK
Supplier: HEATHROW
Supplier: VWR Chemicals
Supplier: VWR Collection
Supplier: VWR Collection
Supplier: VWR Chemicals
Supplier: VWR Chemicals
Supplier: VWR Collection
Supplier: VWR Chemicals
Supplier: VWR Collection